Abstract
Zika virus (ZIKV) belongs to the family of flaviviruses and is transmitted by mosquitoes
of the genus Aedes (A. aegypti and A. albopictus). ZIKV infection in pregnancy can have serious implications on the fetus and the
neonate. Vertical transmission to the fetus can occur irrespective of symptomatic
or asymptomatic infection in the pregnant woman and the risk can persist throughout
pregnancy. The exact frequency of maternal-to-fetal transmission of Zika virus is
difficult to determine accurately. The greatest risk of serious fetal sequelae is
seen if the infection occurs within the first and second trimester. However, they
can also be seen with infections in the third trimester. This document describes the
presentation, feto-maternal manifestations, role of prenatal Ultrasound in diagnosis
of infection, testing methods and the management in pregnancy and screening in the
neonatal period. In the absence of robust evidence as to the definite effects, this
document is aimed at providing practice recommendations for the management of this
infection.
Keywords
Zika virus - Pregnancy - Microcephaly
