Controversy in use of mannitol in head injury

Abrar Ahad Wani; Altaf U Ramzan; Furqan Nizami; Nayil K Malik; A R Kirmani; AR Bhatt; Sarabjeet Singh

doi:10.1016/S0973-0508(08)80022-6

Indian Journal of Neurotrauma, Table of Contents

Indian Journal of Neurotrauma 2008; 05(01): 11-13
DOI: 10.1016/S0973-0508(08)80022-6

Review Article

Thieme Medical and Scientific Publishers Private Ltd.

Controversy in use of mannitol in head injury

Abrar Ahad Wani

,

Altaf U Ramzan

,

Furqan Nizami

,

Nayil K Malik

,

A R Kirmani

,

AR Bhatt

,

Sarabjeet Singh

Subject Editor:

Abstract

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Abstract

The most commonly used drug in the patients of severe head injury is mannitol. The drug is classified pharmacologically as osmotic-diuretic but its mechanism of action in decreasing intracranial pressure is multi-factorial. Despite having dramatic results in the management of head injury patients the drug is still facing many controversies ranging from mechanism of action to the efficacy, especially is the light of evidence based medicine.

Keywords

head injury - mannitol

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References

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