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Homeopathy 2003; 92(02): 99-107
DOI: 10.1016/S1475-4916(03)00016-X
Education and Debate

Antibiotics and the development of resistant microorganisms. Can homeopathy be an alternative?

Petter Viksveen
1   Nordbogaten 10, Stavanger, Norway
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Abstract

Antibiotic resistance is a global public health problem. Once confined primarily to hospitals it is now increasingly common in primary care. The prevalence of resistant bacteria is rising, and organisms resistant to almost all antibiotics have been identified. The main causes are indiscriminate prescribing and the use of antibiotics in animal feeds and other agricultural applications. Policies to restrict use of antibiotics have had limited success. Homeopathy may have a role to play in combating the development of antibiotic resistance. Clinical research suggests that homeopathy is effective in the treatment of upper respiratory tract infections in children, a frequent cause of inappropriate antibiotic prescribing. The EU recommends the use of homeopathy in organic animal husbandry, and it is used by significant numbers of farmers. At present there is little data on the effectiveness of homeopathy in this setting. Further research should be done.

Keywords

homeopathy - antibiotics - resistant microorganisms - infectious diseases - recurring respiratory tract infections


Publication History

Received: 20 August 2002

Accepted: 20 January 2003

Article published online:
16 September 2021

© 2003. Faculty of Homeopathy. This article is published by Thieme.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

  • References

  • 1 Commission of the European Communities, Brussels. , COM(2001) 333 final, Volume I, Communication from the Commission on a community strategy against antimicrobial resistance
    PubMedGoogle Scholar
  • 2 Commission of the European Communities, Brussels. , COM(2001) 333 final, Volume II, Proposal for a Council recommendation on the prudent use of antimicrobial agents in human medicine.
    PubMedGoogle Scholar
  • 3 Hellinger WC. Confronting the problem of increasing antibiotic resistance. South Med J 2000; 93: 842-848
    CrossrefPubMedGoogle Scholar
  • 4 Goossens H. Antibiotic resistance, policy in Belgium. Verh K Acad Geneeskd Belg 2000; 62: 439-469
    PubMedGoogle Scholar
  • 5 Bax R, Mullan N, Verhoef J. The millennium bugs’the need for and development of new antibacterials. Int J Antimicrob Agents 2000; 16: 51-59
    CrossrefPubMedGoogle Scholar
  • 6 WHO annual report, Overcoming Antimicrobial Resistance. 2001
    PubMedGoogle Scholar
  • 7 Hooton TM, Levy SB. Antimicrobial resistance: a plan of action for community practice. Am Fam Physician 2001; 63: 1087-1098 , 1034, 1036, 1039
    PubMedGoogle Scholar
  • 8 Bishai W. Is drug resistance affecting treatment outcomes?. Am J Manag Care 2000; 6 (Suppl 23): S1197-S1201
    PubMedGoogle Scholar
  • 9 Pallasch TJ. Global antibiotic resistance, its impact on the dental community. J Calif Dent Assoc 2000; 28: 215-233
    PubMedGoogle Scholar
  • 10 Pallasch TJ. Global antibiotic resistance, its impact on the dental community. J N J Dent Assoc 2000; 71: 14-5 , 18-9, 22-3 passim
    PubMedGoogle Scholar
  • 11 Blix HS. Antibiotikaforbruk i og utenfor helseinstitusjoner i Norge i 1998. Tidsskr Nor Lægeforen 2000; 120: 1731-1734
    PubMedGoogle Scholar
  • 12 Bacterial resistance to antimicrobial agents in Finland’FINRES 1999. Helsinki: Ministry of Agriculture and Forestry, Ministry of Social Affairs and Health; 1999
    Google Scholar
  • 13 Pal D. Evolution of drug resistance, interpretation of drug sensitivity test. J Indian Med Assoc 2000; 98: 377-380
    PubMedGoogle Scholar
  • 14 Dargatz DA, Traub-Dargatz JL, Sangster NC. Antimicrobic and anthelmintic resistance. Vet Clin North Am Equine Pract 2000; 16: 515-536 , ix–x
    CrossrefPubMedGoogle Scholar
  • 15 Dagan R. Treatment of acute otitis media’challenges in the era of antibiotic resistance. Vaccine 2000; 19 (Suppl 1): S9-S16
    CrossrefPubMedGoogle Scholar
  • 16 Levy SB. Antibiotic, antiseptic resistance: impact on public health. Pediatr Infect Dis J 2000; 19 (Suppl 10): S120-S122
    CrossrefPubMedGoogle Scholar
  • 17 Leclercq R. Safeguarding future antimicrobial options: strategies to minimize resistance. Clin Microbiol Infect 2001; 7 (Suppl 3): 18-23
    PubMedGoogle Scholar
  • 18 Garau J. The hidden impact of antibacterial resistance in respiratory tract infection. Clinical failures: the tip of the iceberg?. Respir Med 2001; 95 (Suppl A): discussion S26–S27 S5-S11
    CrossrefPubMedGoogle Scholar
  • 19 Patterson JE. Antibiotic utilization: is there an effect on antimicrobial resistance?. Chest 2001; 119 (Suppl 2): 426S-430S
    CrossrefPubMedGoogle Scholar
  • 20 van der Waaij D, Nord CE. Development and persistence of multi-resistance to antibiotics in bacteria; an analysis and a new approach to this urgent problem. Int J Antimicrob Agents 2000; 16: 191-197
    CrossrefPubMedGoogle Scholar
  • 21 Loeb M. Antibiotic use in long-term-care facilities: many unanswered questions. Infect Control Hosp Epidemiol 2000; 21: 680-683
    CrossrefPubMedGoogle Scholar
  • 22 Cunha BA. Antibiotic resistance. Med Clin North Am 2000; 84: 1407-1429
    CrossrefPubMedGoogle Scholar
  • 23 Weinstein RA. Controlling antimicrobial resistance in hospitals: infection control and use of antibiotics. Emerg Infect Dis 2001; 7: 188-192
    CrossrefPubMedGoogle Scholar
  • 24 Monroe S, Polk R. Antimicrobial use and bacterial resistance. Curr Opin Microbiol 2000; 3: 496-501
    CrossrefPubMedGoogle Scholar
  • 25 Mah MW, Memish ZA. Antibiotic resistance. An impending crisis. Saudi Med J 2000; 21: 1125-1129
    PubMedGoogle Scholar
  • 26 Clark L. Antibiotic resistance: a growing and multifaceted problem. Br J Nurs 2000; 9: 225-230
    CrossrefPubMedGoogle Scholar
  • 27 Hutchinson JM, Foley RN. Method of physician remuneration and rates of antibiotic prescription. Can Med Assoc J 1999; 160: 1013-1017
    PubMedGoogle Scholar
  • 28 Resistens, nr. 4, 2000. Kommentar: Antibiotika og kunnskapsbasert medisin. . http://www.folkehelsa.no/nyhetsbrev/resistens/2000/4/resistens0400a.html#TopOfPage.
    PubMedGoogle Scholar
  • 29 Ware J. Rational use of antibiotics for upper respiratory infections: an evidence-based approach. Clin Excell Nurse Pract 2000; 4: 151-157
    PubMedGoogle Scholar
  • 30 Giebink GS. Otitis media prevention: non-vaccine prophylaxis. Vaccine 2000; 19 (Suppl 1): S129-S133
    CrossrefPubMedGoogle Scholar
  • 31 Klein JO. The burden of otitis media. Vaccine 2000; 19 (Suppl 1): S2-S8
    CrossrefPubMedGoogle Scholar
  • 32 Mar CD, Glasziou P, Hayem M. Are antibiotics indicated as initial treatment for children with acute otitis media? A meta-analysis. BMJ 1997; 314: 1526-1529
    CrossrefPubMedGoogle Scholar
  • 33 Froom J, Culpepper L, Jacobs M. et al. Antimicrobials for acute otitis media? A review from the International Primary Care Network. BMJ 1997; 315: 98-102
    CrossrefPubMedGoogle Scholar
  • 34 Skadberg BT, Berstad AKH. “Snørr og øreverk”’en plage for barnet, en byrde for samfunnet. Tidsskr Nor Lægeforen 2001; 121: 1328
    PubMedGoogle Scholar
  • 35 Straand J, Rokstad K, Heggedal U. Drug prescribing for children in general practice. A report from the Møre & Romsdal Prescription Study. Acta Pædiatr 1998; 87: 218-224
    CrossrefPubMedGoogle Scholar
  • 36 Myrbakk T, Giæver A, Olsvik Ø, Flægstad T. Antibiotikabehandling av akutt ørebetennelse hos barn. Tidsskr Nor Lægeforen 1999; 119: 2649-2652
    PubMedGoogle Scholar
  • 37 Spiritus E. Antibiotic usage for respiratory tract infection sin an era of rising resistance and increased cost pressure. Am J Manag Care 2000; 6 (Suppl 23): S1216-S1221
    PubMedGoogle Scholar
  • 38 Pichichero ME. Evaluating the need, timing and best choice of antibiotic therapy for acute otitis media and tonsillopharyngitis infections in children. Pediatr Infect Dis J 2000; 19 (Suppl 12): S131-S140
    CrossrefPubMedGoogle Scholar
  • 39 Longworth DL. Microbial drug resistance, the roles of the new antibiotics. . Department of Infectious Diseases, Clevel and Clinic Foundation, OH 44195, USA.
    PubMedGoogle Scholar
  • 40 Kværner KJ, Mair IW. Akutt og residiverende akutt otitis media. Profylakse og behandling i lys av nyere kunnskap. Tidsskr Nor Lægeforen 1997; 117: 4096-4098
    PubMedGoogle Scholar
  • 41 Degener JE. The consequences of bacterial resistance to antibiotics. De gevolgen van bacteriele resistentie tegen antibiotica. . GeneesmiddelenBulletin (GeBu). Jaargang 33’Juni 1999’No. 6.
    PubMedGoogle Scholar
  • 42 Flottorp S, Oxman AD, Cooper JG, Hjortdahl P, Sandberg S, Vorland LH. Retningslinjer for diagnostikk og behandling av sår hals. Tidsskr Nor Lægeforen 2000; 120: 1754-1760
    PubMedGoogle Scholar
  • 43 World Health Organisation annual report 2000. . Overcoming Antimicrobial Resistance World Health Report on Infectious Diseases 2000. Available at: http://www.who.int/infectious-disease-report/2000/index.html.
    PubMedGoogle Scholar
  • 44 WHO. Containing antimicrobial resistance. . WHO/CDS/CSR/DRS/99.2. Geneva: World Health Organisation, 1999.
    PubMedGoogle Scholar
  • 45 Blondeau JM, Vaughan D. A review of antimicrobial resistance in Canada. Can J Microbiol 2000; 46: 867-877
    CrossrefPubMedGoogle Scholar
  • 46 Viksveen P, Gordon S. The future of the practice of homeopathy in Europe. Homoeopathic Links 2002; 15: 77-79
    PubMedGoogle Scholar
  • 47 Norges offentlige utredninger, NOU 1998:21 Alternativ medisin. . (Official report published by the Norwegian Department of Health. Available at: http://odin.dep.no/hd/norsk/publ/utredninger/NOU/030005-020019/index-ved005-b-n-a.html).
    PubMedGoogle Scholar
  • 48 Resolution on the Commission report to the European Parliament and the Council on the application of Directives 92/73/EEC and 92/74/EEC on homeopathic medicinal products. (COM(97)0362 - C4-0484/97).
    PubMedGoogle Scholar
  • 49 Viksveen P, Finne B. A survey of 10 countries where homeopathy is being practised. . European Council for Classical Homeopathy, March 1999. Available at: European Council for Classical Homeopathy, School House, Market Place, Kenninghall, Norfolk NR16 2AH, UK. www.homeopathy-ecch.org.
    PubMedGoogle Scholar
  • 50 Maddalena S. The legal status of complementary medicines in Europe’a comparative analysis. . Bern, Stämpfli, 1999.
    PubMedGoogle Scholar
  • 51 Menniti-Ippolito F, Gargiulo L, Bologna E, Forcella E, Raschetti R. Use of unconventional medicine in Italy: a nation-wide survey. Eur J Clin Pharmacol 2002; 58: 61-64
    CrossrefPubMedGoogle Scholar
  • 52 Encyclopedia Britannica. . Available at: http://www.britannica.com/search?query=homeopathy&ct=.
    PubMedGoogle Scholar
  • 53 Legal Status of Traditional Medicine and Complementary/Alternative Medicine: A Worldwide Review. , World Health Organization, 2001.
    PubMedGoogle Scholar
  • 54 Ahuja MC, Khamar B. Antibiotic associated diarrhoea: a controlled study comparing plain antibiotic with those containing protected lactobacilli. J Indian Med Assoc 2002; 100: 334-335
    PubMedGoogle Scholar
  • 55 Maxwell PR, Rink E, Kumar D, Mendall MA. Antibiotics increase functional abdominal symptoms. Am J Gastroenterol 2002; 97: 104-108
    CrossrefPubMedGoogle Scholar
  • 56 Homeopati eller antibiotika’du kan velge (leaflet). . Available at: Norske Homeopaters Landsforbund, Storg. 39, 0182 Oslo, Norway.
    PubMedGoogle Scholar
  • 57 Linde K, Clausius N, Ramirez G. et al. Are the clinical effects of homoeopathy placebo effects? A meta-analysis of placebo-controlled trials. Lancet 1997; 350: 834-843
    CrossrefPubMedGoogle Scholar
  • 58 Kvaerner KJ, Nafstad P, Jaakkola JJ. Upper respiratory morbidity in preschool children: a cross-sectional study. Arch Otolaryngol Head Neck Surg 2000; 126: 1201-1206
    CrossrefPubMedGoogle Scholar
  • 59 Monto AS, Sullivan KM. Acute respiratory illness in the community. Frequency of illness and the agents involved. Epidemiol Infect 1993; 110: 145-160
    CrossrefPubMedGoogle Scholar
  • 60 Wefring KW, Lie KK. Tett i nesen og vondt i øret–øvre luftveisinfeksjoner hos fireåringer. Tidsskr Nor Lægeforen 2001; 121: 1329-1332
    PubMedGoogle Scholar
  • 61 Rokstad K, Straand J, Sandvik H. Pasientkontakter i allmennpraksis. Tidsskr Nor Lægeforen 1997; 117: 659-664
    PubMedGoogle Scholar
  • 62 Reid S. A survey of the use of over-the-counter homeopathic medicines purchased in health stores in central Manchester. Homeopathy 2002; 91: 225-229
    Article in Thieme ConnectPubMedGoogle Scholar
  • 63 Friese K-H, Kruse S, Ludtke R, Moeller H. Homeopathic treatment of otitis media in children: comparisons with conventional therapy. Int J Clin Pharmacol Ther 1997; 35: 296-301
    PubMedGoogle Scholar
  • 64 Lærum E, Borchgrevink CF, Wiens G. Hvem går til homøopat?. Tidsskr Nor Lægeforen 1985; 105: 2478-2482
    PubMedGoogle Scholar
  • 65 Steinsbekk A. Fønnebø V. Users of homeopaths in Norway in 1998, compared to previous users and GP patients. Homeopathy 2003; 92: 1-64
    Article in Thieme ConnectPubMedGoogle Scholar
  • 66 Steinsbekk A. Hvilke plager har barn som oppsøker norske homøopater?. Dynamis 2001; 2: 28-31
    PubMedGoogle Scholar
  • 67 Andersen HE. En undersøgelse af Klassisk Homøopati. Teorier, praksis og brugererfaringer. 1999. ISBN 87-987279-0-7
    PubMedGoogle Scholar
  • 68 de Lange de Klerk E. et al. Effects of homoeopathic medicines on daily burden of symptoms in children with recurrent upper respiratory tract infections. BMJ 1994; 309: 1329-1332
    CrossrefPubMedGoogle Scholar
  • 69 Riley D, Fischer M, Singh B, Haidvogl M, Heger M. Homeopathy and conventional medicine: an outcomes study comparing effectiveness in a primary care setting. J Altern Complement Med 2001; 7: 149-159
    CrossrefPubMedGoogle Scholar
  • 70 Jacobs J, Springer DA, Crothers D. Homeopathic treatment of acute otitis media in children: a preliminary randomized placebo-controlled trial. Pediatr Infect Dis J 2001; 20: 177-183
    CrossrefPubMedGoogle Scholar
  • 71 Frei H, Thurneysen A. Homeopathy in acute otitis media in children: treatment effect or spontaneous resolution?. Br Homeopath J 2001; 90: 180-182
    Article in Thieme ConnectPubMedGoogle Scholar
  • 72 Harrison H, Fixsen A, Vickers A. A randomized comparison of homoeopathic, standard care for the treatment of glue ear in children. Compl Therap Med 1999; 7: 132-135
    PubMedGoogle Scholar
  • 73 Weber U, Luedtke R, Friese KH, Fischer I, Moeller H. A non-randomised pilot study to compare complementary and conventional treatments of acute sinusitis. Forsch Komplementarmed Klass Naturheilkd 2002; 9: 99-104
    PubMedGoogle Scholar
  • 74 Adler M. Efficacy, safety of a fixed-combination homeopathic therapy for sinusitis. Adv Ther 1999; 16: 103-111
    PubMedGoogle Scholar
  • 75 Wiesenauer M, Gaus W, Bohnacker U, Haussler S. [Efficiency of homeopathic preparation combinations in sinusitis. Results of a randomized double blind study with general practitioners.]. Arzneimittelforschung 1989; 39: 620-625
    PubMedGoogle Scholar
  • 76 van Haselen R. The economic evaluation of complementary medicine: a staged approach at the Royal London Homeopathic Hospital. Br Homeopath J 2000; 89 (Suppl 1): S23-S26
    Article in Thieme ConnectPubMedGoogle Scholar
  • 77 Buxton M. Assessing the cost-effectiveness of homeopathic medicines: are the problems different from other health technologies?. Br Homeopath J 2000; 89 (Suppl 1): S20-S22
    Article in Thieme ConnectPubMedGoogle Scholar
  • 78 Chaufferin G. Improving the evaluation of homeopathy: economic considerations and impact on health. Br Homeopath J 2000; 89 (Suppl 1): S27-S30
    Article in Thieme ConnectPubMedGoogle Scholar
  • 79 Swayne J. The cost, effectiveness of homoeopathy. A pilot study, proposals for future research. Br Homoeopath J 1992; 81: 148-150
    Article in Thieme ConnectPubMedGoogle Scholar
  • 80 Schafer T, Riehle A, Wichmann HE, Ring J. Alternative medicine in allergies’prevalence, patterns of use, and costs. Allergy 2002; 57: 694-700
    CrossrefPubMedGoogle Scholar
  • 81 Christie EA, Ward AT. Report on NHS practice-based homoeopathy project. . Analysis of effectiveness and cost of homoeopathic treatment within ad GP practice at St. Margaret's Surgery, Bradford on Avon, Wilts. September 1996. The Society of Homeopaths. ISBH 1 901262 006.
    PubMedGoogle Scholar
  • 82 Kastebrink S-E. Studie av homeopatiskt behandlade kor med diverse åkommor. . Report, 1996. May be ordered from the author at tel: + 45 586 73 20 06.
    PubMedGoogle Scholar
  • 83 Henriksson E. Homeopatibehandling på mjölkkor. . Examensarbete i Lantmästarprogrammet. Alnarp: Inst. för jordbrukets biosystem och teknologi, 1997.
    PubMedGoogle Scholar
  • 84 Loor H. Homeopati på ko - en ny behandlingsmetod i mjölkproduktionen?. Institutionen för idisslarmedicin och epidemiologi SLU, Uppsala, 1997.
    PubMedGoogle Scholar
  • 85 Arnesson P, Jörgenfelt C, och Larsson L. Dokumentation av homeopati för nötkreatur. Report, 1999. Available at: Lisbeth Larsson, tel. + 46 504 300 11
    PubMedGoogle Scholar
  • 86 ECCH report on the homeopathic treatment of animals in Europe, June 2000. Available at: European Council for Classical Homeopathy, School House, Market Place, Kenninghall, Norfolk NR16 2AH, UK. www.homeopathy-ecch.org
    PubMedGoogle Scholar
  • 87 Council Regulation (EC) No 1804/1999 of 19 July 1999 supplementing Regulation EC No 2092/91 on organic production of agricultural products and indications referring there on agricultural products and foodstuffs to include livestock production..
    PubMedGoogle Scholar
  • 88 Fossing EC. vet.med. Application of alternative medicine in organic dairy herds with special emphasis on the effect of veterinary homeopathy on udder health. . Project description available at: http://www.raph.dk/common/phd/student-profiles/elisabeth_christine_fossing/index.php3.
    PubMedGoogle Scholar
  • 89 Albrecht H. Schütte A. Homeopathy versus antibiotics in metaphylaxis of infectious diseases: a clinical study in pig fattening and its significance to consumers. Altern Ther Health Med 1999; 5: 64-68
    PubMedGoogle Scholar
  • 90 Vaarst M. The challenge of implementing homoeopathy into the health advisory system in organic herds. . Danish experiences. Veterinary homoeopathy in organic herds, 1997. Rapport no 90, Ministeriet for Fødevarer, Landbrug og Fiskeri, Danmarks Jordbrugsforksning. Printed at Research Centre Foulum.
    PubMedGoogle Scholar
  • 91 Henriksen B. Stor interesse for homeopati og urtemedisin hos norske økobønder. . Praksisnytt. Volume 7, nr. 1, Mars 2002. s 55-58.
    PubMedGoogle Scholar
  • 92 Persson Waller K, Beyer W, och Ekman T. Veterinär homeopati till lantbrukets djur - en sammanställning av vetenskapliga försök, Institutionen för obstetrik och gynekologi, Rapport, SLU, Uppsala, 1998. . ISBN 91-576-5570-7.
    PubMedGoogle Scholar