Multiple Choice Question – Pharmacotherapy of Epilepsy

• Q.1 Genetic mutation which is NOT associated with Dravet syndrome is

  • A) SCN 2A

  • B) SCN 1B

  • C) CACN 1A

  • D) GABARG2

• Q.2 All are true regarding Ring 20 chromosome syndrome except

  • A) NCSE of frontotemporal origin

  • B) Microcephaly is a usual accompaniment

  • C) Nocturnal CSWS is not a point of exclusion

  • D) Profound intellectual dysfunction may be seen

• Q.3 Absence seizures are seen in what percentage of JME

  • A) 5%

  • B) 10%

  • C) 30%

  • D) 50%

• Q.4 Mechanism of action of Perampanel is through

  • A) AMPA receptor antagonism

  • B) AMPA receptor facilitation

  • C) Potassium channel blocking

  • D) Prolonging sodium channel inactivation

• Q.5 Which among the following differentiates nocturnal frontal lobe epilepsy from parasomnias

  • A) Coherent speech with no recall

  • B) Duration more than 10 minutes

  • C) Wandering outside room

  • D) Five or more events in a single night

Dr. Deepak Menon and Dr. Sanjeev V. Thomas