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DOI: 10.1016/j.homp.2003.10.003
Action of Causticum in inflammatory models
Publication History
Received28 March 2003
revised03 June 2003
accepted22 October 2003
Publication Date:
22 December 2017 (online)
![](https://www.thieme-connect.de/media/10.1055-s-00034926/200401/lookinside/thumbnails/10-1016-j-homp-2003-10-003-1.jpg)
Abstract
The anti-inflammatory effect of Causticum was evaluated using acute and chronic inflammatory models in vivo. The administration of concentrated Causticum solution into the hind paw of rats produced an inflammatory reaction with oedema formation within the first hour, showing that Causticum acts as an oedematogenic agent. Carrageenin induced rat paw oedema was significantly inhibited (P<0.05) in the group treated with Causticum 30cH solution compared to control. Groups treated with potentized Causticum (6cH, 12cH, 30cH and 200cH), showed significant inhibition (P<0.05) of the inflammation pre-induced by carrageenin. However pre-treatment with Causticum 30cH for 6 days (0.5 ml, daily) did not significantly inhibit granulation using an implantation method.
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