Anti-inflammatory activity of Arnica montana 6cH: preclinical study in animals

S.B Macêdo; L.R Ferreira; F.F Perazzo; J.C Tavares Carvalho

doi:10.1016/j.homp.2004.02.006

Homeopathy, Table of Contents

Homeopathy 2004; 93(02): 84-87
DOI: 10.1016/j.homp.2004.02.006

Original Paper

Anti-inflammatory activity of Arnica montana 6cH: preclinical study in animals

S.B Macêdo

¹Faculdade de Odontologia, Pontifı́cia Universidade Católica de Brası́lia, Brası́lia, Brazil

,

L.R Ferreira

²Instituto de Med. Veterinária, Campus Poços de Caldas, Pontifı́cia Universidade Católica de Poços de Caldas, Minas Gerais, Brazil

,

F.F Perazzo

³Laboratório de Fitofármacos, Universidade de Alfenas, Rod. MG 179, km 0, CP 23, CEP 37130-000, Alfenas, Minas Gerais, Brazil

,

J.C Tavares Carvalho

³Laboratório de Fitofármacos, Universidade de Alfenas, Rod. MG 179, km 0, CP 23, CEP 37130-000, Alfenas, Minas Gerais, Brazil

⁴Faculdade de Ciências da Saúde de São Paulo (FACIS-IBEHE), S. Paulo, Brazil

› Author Affiliations
Subject Editor:

Abstract

The anti-inflammatory effect of Arnica montana 6cH was evaluated using acute and chronic inflammation models. In the acute, model, carrageenin-induced rat paw oedema, the group treated with Arnica montana 6cH showed 30% inhibition compared to control (P<0.05). Treatment with Arnica 6cH, 30 min prior to carrageenin, did not produce any inhibition of the inflammatory process. In the chronic model, Nystatin-induced oedema, the group treated 3 days previously with Arnica montana 6cH had reduced inflammation 6 h after the inflammatory agent was applied (P<0.05). When treatment was given 6 h after Nystatin treatment, there was no significant inhibitory effect. In a model based on histamine-induced increase of vascular permeability, pretreatment with Arnica montana 6cH blocked the action of histamine in increasing vascular permeability.

Keywords

Arnica montana 6 cH - anti-inflammatory activity - preclinical

Full Text

References

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