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Endoscopy 2018; 50(12): 1175-1179
DOI: 10.1055/a-0620-8403
Innovations and brief communications
© Georg Thieme Verlag KG Stuttgart · New York

A novel technique using high energy synchronous double-wave laser in endoscopic submucosal dissection of patients with superficial esophageal neoplasm

Jun Yao   *
1   Department of Gastroenterology, Shenzhen People’s Hospital, Guangdong Province, China
,
Jun Li   *
2   Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai, China
,
Peng Wang
2   Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai, China
,
Feng Liu
2   Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai, China
,
Zhaoshen Li
2   Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai, China
› Author Affiliations
Further Information

Publication History

submitted 23 November 2017

accepted after revision 16 March 2018

Publication Date:
08 June 2018 (online)

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Abstract

Background Endoscopic submucosal dissection (ESD) has been widely used to treat superficial esophageal neoplasms (SENs). Intraoperative bleeding is one of the main concerns that makes ESD in the esophagus more difficult and time consuming with higher complication rates. We introduced a novel laser endoknife system that enabled better intraoperative hemostasis, and preliminarily investigated its feasibility in ESD for patients with SENs.

Methods 17 consecutive patients with SENs were prospectively enrolled. The laser endoknife system was used in marking and submucosal dissection. Data on therapeutic outcomes were collected and analyzed.

Results The median diameter of the lesions was 2.5 cm and of the resected specimens was 3.0 cm. The median procedure time was 48 minutes. Histologic evaluation revealed 15 high grade intraepithelial neoplasias and two squamous cell carcinomas. No intraoperative bleeding occurred during laser cutting and no significant complications occurred postoperatively. Curative R0 resection was achieved in all patients.

Conclusions Our new laser endoknife system was feasible in the submucosal dissection of SENs and showed great prospects for future application.

* These authors contributed equally to this work.


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