Aktuelle mikrobiologische Methoden zur Bestimmung des Kariesrisikos

Nach dem Durcharbeiten des Artikels sollte der Leser
▪ die Grundlagen der Kariesentstehung reflektiert haben,
▪ den Nutzen der Kariesrisikobestimmung einschätzen können,
▪ den Speichel als mögliches Markermedium zukünftiger wissenschaftlicher Einteilungen beurteilen können.

• Literatur

• 1 Keyes PH. The infectious and transmissible nature of experimental dental caries. Findings and implications. Arch Oral Biol 1960; 1: 304-320
• 2 Wong A, Subar PE, Young DA. Dental Caries: An Update on dental Trends and Therapy. Adv Pediatr 2017; 64: 307-330
• 3 Young DA, Nový BB, Zeller GG. et al. The American Dental Association Caries Classification System for clinical practice: a report of the American Dental Association Council on Scientific Affairs. J Am Dent Assoc 2015; 146: 79-86
• 4 Beighton D, Al-Haboubi M, Mantzourani M. et al. Oral Bifidobacteria: caries-associated bacteria in older adults. J Dent Res 2010; 89: 970-974
• 5 Kutsch VK. Dental caries: an updated medical model of risk assessment. J Prosthet Dent 2014; 111: 280-285
• 6 Tanner AC, Mathney JM, Kent RL. et al. Cultivable anaerobic microbiota of severe early childhood caries. J Clin Microbiol 2011; 49: 1464-1474
• 7 Wolff D, Frese C, Maier-Kraus T. et al. Bacterial biofilm composition in caries and caries-free subjects. Caries Res 2013; 47: 69-77
• 8 Aas JA, Griffen AL, Dardis SR. et al. Bacteria of dental caries in primary and permanent teeth in children and young adults. J Clin Microbiol 2008; 46: 1407-1417
• 9 Fontana M, Zero DT. Assessing patientsʼ caries risk. J Am Dent Assoc 2006; 137: 1231-1239
• 10 Twetman S, Fontana M. Patient caries risk assessment. Monogr Oral Sci 2009; 21: 91-101
• 11 Thenisch NL, Bachmann LM, Imfeld T. et al. Are mutans streptococci detected in preschool children a reliable predictive factor for dental caries risk? A systematic review. Caries Res 2006; 40: 366-374
• 12 Hellwege KD. Die Praxis der zahnmedizinischen Prophylaxe: Ein Leitfaden f. d. Individual-, Gruppenprophylaxe u. initiale Parodontaltherapie (ZMK Praxis). Stuttgart: Thieme; 2003: 312
• 13 Belstrøm D, Holmstrup P, Bardow A. et al. Comparative analysis of bacterial profiles in unstimulated and stimulated saliva samples. J Oral Microbiol 2016; 8: 30112
• 14 Fejerskov O, Kidd E. Dental Caries: The Disease and its clinical Management. 2nd edition. New Jersey: Wiley-Blackwell; 2008
• 15 Dawes C. Salivary flow patterns and the health of hard and soft oral tissues. J Am Dent Assoc 2008; 139 (Suppl.) 18S-24S
• 16 Guo L, Shi W. Salivary biomarkers for caries risk assessment. J Calif Dent Assoc 2013; 41: 107-109 112–108
• 17 Gao X, Jiang S, Koh D. et al. Salivary biomarkers for dental caries. Periodontol 2000 2016; 70: 128-141
• 18 Kaufman E, Lamster IB. The diagnostic applications of saliva – a review. Crit Rev Oral Biol Med 2002; 13: 197-212
• 19 Arbeitsgemeinschaft Zahngesundheit für die Stadt Heidelberg und den Rhein-Neckar-Kreis (AGZ-RNK). Kariesrisikotest (Speicheltest). Im Internet: http://www.agz-rnk.de/agz/content/3/3_2/3_2_6/3_2_6_1/index.php Stand: 01.11.2018
• 20 Gu F, Li Y, Zhou C. et al. Bacterial 16S rRNA/rDNA profiling in the liquid Phase of human Saliva. Open Dent J 2009; 3: 80-84
• 21 Yang F, Zeng X, Ning K. et al. Saliva microbiomes distinguish caries-active from healthy human populations. ISME J 2012; 6: 1-10
• 22 Childers NK, Osgood RC, Hsu KL. et al. Real-time quantitative polymerase chain reaction for enumeration of Streptococcus mutans from oral samples. Eur J Oral Sci 2011; 119: 447-454