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Nervenheilkunde 2019; 38(03): 108-114
DOI: 10.1055/a-0818-9117
Schwerpunkt
Georg Thieme Verlag KG Stuttgart · New York

Neuromuskuläre Erkrankungen und Schlaf

Sleep and neuromuscular disorders
Jens Spießhöfer
1   Institut für Schlafmedizin und Neuromuskuläre Erkrankungen, Universitätsklinikum Münster
,
Peter Young
1   Institut für Schlafmedizin und Neuromuskuläre Erkrankungen, Universitätsklinikum Münster
,
Matthias Boentert
1   Institut für Schlafmedizin und Neuromuskuläre Erkrankungen, Universitätsklinikum Münster
› Institutsangaben
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Publikationsverlauf

Publikationsdatum:
18. März 2019 (online)

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Zusammenfassung

Viele neuromuskuläre Erkrankungen (NME) sind mit Begleitsymptomen verbunden, die den Schlaf und die Schlafqualität beeinträchtigen. Schlafstörungen können eine unspezifische Folge der Immobilisierung darstellen, aber besonders bei Erkrankungen des peripheren Nervensystems auch auf nächtliche Crampi oder ein Restless-legs-Syndrom zurückzuführen sein. Motoneuronerkrankungen, akute Immunneuropathien und viele Myopathien können im Verlauf mit einer relevanten Schwäche der Atemmuskulatur einhergehen, die sich initial als schlafbezogene Hypoventilation manifestiert und bis zur hyperkapnischen respiratorischen Insuffizienz voranschreiten kann. Zahlreiche Erkrankungen sind zudem mit einem erhöhten Risiko für eine obstruktive Schlafapnoe assoziiert. Schlafbezogene Symptome sind bei NME häufig und sollten gezielt erfragt werden, um eine geeignete Diagnostik und Therapie zu ermöglichen.

Abstract

Many neuromuscular disorders (NMD) are associated with symptoms that affect sleep and sleep quality. Sleep disturbances can be unspecifically caused by immobilization or pain, but also by nocturnal leg cramps or secondary restless legs syndrome in peripheral neuropathies, in particular. Motor neuron disease, acute immune neuropathies, and many myopathies often lead to significant respiratory muscle weakness, which initially presents as sleep-related hypoventilation and may exacerbate to hypercapnic respiratory failure. Many conditions are associated with an increased risk for obstructive sleep apnea. Sleep-related symptoms are common in NMD and should be specifically sought in order to take adequate diagnostic and therapeutic measures.

Schlüsselwörter

Neuromuskuläre Erkrankungen - Schlaf - Schlafstörungen - Schlafapnoe - Hypoventilation

Key words

Neuromuscular disorders - sleep - sleep disorders - sleep apnea - hypoventilation
 

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