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Aktuelle Dermatologie 2019; 45(07): 325-331
DOI: 10.1055/a-0881-6976
Übersicht
© Georg Thieme Verlag KG Stuttgart · New York

Phytotherapie bei entzündlichen Hauterkrankungen

Phytotherapy for Inflammatory Skin Diseases
J. Hoffmann
Klinik für Dermatologie und Venerologie, Universitätsklinikum Freiburg, Freiburg
,
U. Wölfle
Klinik für Dermatologie und Venerologie, Universitätsklinikum Freiburg, Freiburg
,
C. Schempp
Klinik für Dermatologie und Venerologie, Universitätsklinikum Freiburg, Freiburg
› Author Affiliations
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Publication History

Publication Date:
16 July 2019 (online)

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Zusammenfassung

In den letzten Jahren wurden einige neue pflanzliche Arzneimittel, Medizinprodukte und Hautpflegemittel für die topische Behandlung von entzündlichen Hauterkrankungen entwickelt. Besonders gut belegt ist die Wirksamkeit von Inhaltsstoffen aus dem Süßholz bei der atopischen Dermatitis und von Indigoextrakten bei der Psoriasis. Ein neuer vielversprechender Therapieansatz zur äußerlichen Behandlung einer geschädigten Hautbarriere sind Bitterstoffe, die an Bitterstoffrezeptoren der Haut binden und die Keratin- und Lipidsynthese der Keratinozyten anregen. Weitere pflanzliche Wirkstoffe für die Behandlung von Rosazea und Akne vulgaris werden ebenfalls besprochen.

Abstract

During the last years several new herbal drugs, medical products and cosmetics were developed for the treatment of inflammatory skin diseases. The best studied botanicals are licorice extract for atopic dermatitis and indigo extract for psoriasis. Bitter agents are new promising active ingredients for the topical treatment of skin conditions with an impaired skin barrier. Bitter agents bind to epidermal bitter taste receptors that stimulate the formation of keratins and lipids in keratinocytes. Botanical treatments for the treatment of rosacea and acne vulgaris are also discussed.

 

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