Primary Therapy of Early Breast Cancer: Evidence, Controversies, Consensus

Michael Untch; Christoph Thomssen; Ingo Bauerfeind; Michael Braun; Sara Y. Brucker; Ricardo Felberbaum; Friederike Hagemann; Renate Haidinger; Arnd Hönig; Jens Huober; Christian Jackisch; Hans-Christian Kolberg; Cornelia Kolberg-Liedtke; Thorsten Kühn; Diana Lüftner; Nicolai Maass; Toralf Reimer; Andreas Schneeweiss; Eva Schumacher-Wulf; Florian Schütz; Marc Thill; Rachel Wuerstlein; Peter A. Fasching; Nadia Harbeck

doi:10.1055/a-0897-6457

Geburtshilfe und Frauenheilkunde, Table of Contents

CC BY-NC-ND 4.0 · Geburtshilfe Frauenheilkd 2019; 79(06): 591-604
DOI: 10.1055/a-0897-6457

GebFra Science

Review/Übersicht

Georg Thieme Verlag KG Stuttgart · New York

Primary Therapy of Early Breast Cancer: Evidence, Controversies, Consensus

Spectrum of Opinion of German Specialists on the 16th St. Gallen International Breast Cancer Conference (Vienna 2019) Article in several languages: English | deutsch

Michael Untch^*

¹Klinik für Gynäkologie und Geburtshilfe, interdisziplinäres Brustzentrum, HELIOS Klinikum Berlin Buch, Berlin, Germany

,

Christoph Thomssen^*

²Klinik und Poliklinik für Gynäkologie, Martin-Luther-Universität, Halle-Wittenberg, Halle/Saale, Germany

,

Ingo Bauerfeind^**

³Interdisziplinäres Brustkrebszentrum, Frauenklinik, Klinikum Landshut, Landshut, Germany

,

Michael Braun^**

⁴Interdisziplinäres Brustzentrum, Frauenklinik, Rotkreuzklinikum München, München, Germany

,

Sara Y. Brucker^*^#

⁵Universitäts-Frauenklinik Tübingen, Tübingen, Germany

,

Ricardo Felberbaum^**

⁶Interdisziplinäres Brustzentrum Kempten – Allgäu (IBZK-A), Klinik für Frauenheilkunde und Geburtshilfe, Klinikum Kempten, Klinikverbund Kempten-Oberallgäu, Kempten, Germany

,

Friederike Hagemann^**

⁷Brustzentrum, Frauenklinik der Universität München (LMU), München, Germany

,

Renate Haidinger^**

⁸Brustkrebs Deutschland e. V.

,

Arnd Hönig^**

⁹Brustzentrum, Frauenklinik, Katholisches Klinikum Mainz, Mainz, Germany

,

Jens Huober^*^#

¹⁰Universitätsfrauenklinik Ulm, Brustzentrum, Ulm, Germany

,

Christian Jackisch^*

¹¹Klinik für Gynäkologie und Geburtshilfe, Sana-Klinikum Offenbach, Offenbach, Germany

,

Hans-Christian Kolberg^**

¹²Brustzentrum, Klinik für Gynäkologie und Geburtshilfe, Marienhospital Bottrop gGmbH, Bottrop, Germany

,

Cornelia Kolberg-Liedtke^*

¹³Charité – Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany

,

Thorsten Kühn^*

¹⁴Klinik für Frauenheilkunde und Geburtshilfe, Klinikum Esslingen, Esslingen, Germany

,

Diana Lüftner^*

¹⁵Medizinische Klinik mit Schwerpunkt Hämatologie, Onkologie und Tumorimmunologie, Charité Campus Benjamin Franklin, Berlin, Germany

,

Nicolai Maass^**

¹⁶Brustzentrum, Klinik für Gynäkologie und Geburtshilfe, Universitätsklinikum Schleswig-Holstein, Kiel, Germany

,

Toralf Reimer^**

¹⁷Brustzentrum, Universitätsfrauenklinik und Poliklinik, Klinikum Südstadt Rostock, Rostock, Germany

,

Andreas Schneeweiss^*

¹⁸Sektionsleiter Gynäkologische Onkologie des Universitätsklinikum (UKHD), Fellow des Deutschen Krebsforschungszentrum (DKFZ), Nationales Centrum für Tumorerkrankungen (NCT), Universitätsklinikum Heidelberg, Heidelberg, Germany

,

Eva Schumacher-Wulf^**

¹⁹Mamma Mia! Das Brustkrebsmagazin, Kronberg, Germany

,

Florian Schütz^**

²⁰Brustzentrum, Sektion Senologie, UniversitätsKlinikum Heidelberg, Heidelberg, Germany

,

Marc Thill^*

²¹Klinik für Gynäkologie und Gynäkologische Onkologie, Agaplesion Markus Krankenhaus, Frankfurt/Main, Germany

,

Rachel Wuerstlein^**

⁷Brustzentrum, Frauenklinik der Universität München (LMU), München, Germany

,

Peter A. Fasching^*

²²Frauenklinik des Universitätsklinikums Erlangen, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany

,

Nadia Harbeck^*^#

⁷Brustzentrum, Frauenklinik der Universität München (LMU), München, Germany

› Author Affiliations

Abstract

The results of the international St. Gallen Consensus Conference for the treatment of patients with primary breast cancer were discussed this year by a working group of leading breast cancer experts in view of the therapy recommendations for everyday clinical practice in Germany. Three of the breast cancer experts are also members of this yearʼs St. Gallen panel. The comparison of the St. Gallen recommendations with the annually updated treatment recommendations of the AGO 2019 as well as the S3 guideline is useful, since the recommendations of the St. Gallen panel represent the opinions of experts from various countries and disciplines. The recommendations of the S3 guideline and AGO are based on evidence-based research of the literature. This yearʼs 16th St. Gallen conference featured the motto “Magnitude of clinical benefit”. In addition to the evidence-based data, each therapeutic decision must also undergo a benefit/risk assessment of the patientʼs individual situation and be discussed with the patient.

Key words

St. Gallen consensus 2019 - early breast cancer - locoregional therapy - axilla - neoadjuvant treatment - systemic therapy

Full Text

References

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