Konservative Pyometrabehandlung bei Hund und Katze

Die Pyometra hat einen hohen Stellenwert in der täglichen klinischen Praxis mit einer Inzidenz von 15% [1] bis 25% [2] bei der Hündin und ca. 2% bei der Kätzin [3]. Sie stellt damit die häufigste Uteruserkrankung beim Kleintier und als potenziell lebensbedrohliche Erkrankung einen Notfall dar [4].

• Literatur

• 1 Fukuda S. Incidence of pyometra in colony-raised beagle dogs. Exp Anim 2001; 50 (04) 325-329
• 2 Egenvall A, Hagman R, Bonnett BN. et al. Breed risk of pyometra in insured dogs in Sweden. J Vet Intern Med 2001; 15 (06) 530-538
• 3 Hagman R. Pyometra in small animals. Vet Clin North Am Small Anim Pract 2018; 48: 639-661
• 4 Blendinger K. Die Pyometra der Hündin – eine Übersicht. Kleintier konkret 2016; 3: 24-33
• 5 Paschke C, Schade J, Wehrend A. Pyometra bei der Hündin. Prakt Tierarzt 2014; 95 (Suppl. 04) 3-14
• 6 Fieni F, Topie E, Gogny A. Medical treatment for pyometra in dogs. Reprod Domest Anim 2014; 49 (Suppl. 02) 28-32
• 7 Gogny A, Fiéni F. Aglepristone: A review on its clinical use in animals. Theriogenology 2016; 85: 555-566
• 8 Wehrend A. Ausfluss aus der Rima vulvae. In: Wehrend A. Leitsymptome Gynäkologie und Geburtshilfe beim Hund. Stuttgart: Enke; 2010: 100
• 9 Jurka P, Max A, Hawrynska K. et al. Age-related pregnancy results and further examination of bitches after aglepristone treatment of pyometra. Reprod Dom Anim 2010; 45: 525-529
• 10 Trasch K, Wehrend A, Bostedt H. Follow-up examinations of bitches after conservative treatment of pyometra with the antigestan aglepristone. J Vet Med A Physiol Pathol Clin Med 2003; 50: 375-379
• 11 Galac S, Kooistra HS, Dieleman SJ. et al. Effects of aglepristone, a progesterone receptor antagonist, administered during the early luteal phase in non-pregnant bitches. Theriogenology 2004; 62: 494-500
• 12 Bostedt H. Pyometra-Komplex. In: Günzel-Apel AR, Bostedt H. Hrsg. Reproduktionsmedizin und Neonatologie von Hund und Katze. Stuttgart: Schattauer; 2016: 146
• 13 Contri A, Gloria A, Carluccio A. et al. Effectiveness of a modified administration protocol for the medical treatment of canine pyometra. Vet Res Commun 2015; 39: 1-5
• 14 Nak D, Nak Y, Tuna B. Follow-up examinations after medical treatment of pyometra in cats with the progesterone-antagonist aglepristone. J Feline Med Surg 2009; 11: 499-502
• 15 Hollinshead F, Krekeler N. Pyometra in the queen: To spay or not to spay?. J Feline Med Surg 2016; 18: 21-33
• 16 Metcalfe S, Vischer C. Medical treatment of pyometra and the use of aglepristone. Aust Vet Pract 2006; 36: 171-174
• 17 Ros L, Holst BS, Hagman R. A retrospective study of bitches with pyometra, medically treated with aglepristone. Theriogenology 2014; 82: 1281-1286
• 18 Romagnoli S. Canine pyometra: pathogenesis, therapy and clinical cases. Granada, Spain: 27^th WSAVA Congress; 2002: 12-16
• 19 Engelhardt von AB. Treatment of the metritis/pyometra complex with aglepristone in a guinea pig. Prakt Tierarzt 2006; 87 (01) 14-17
• 20 Pisu MC, Andolfatto A, Veronesi MC. Pyometra in a six-month-old nulliparous golden hamster (Mesocricetus auratus) treated with aglepristone. Vet Q 2012; 32 (3 – 4): 179-181
• 21 Kersey R, LeMelledo D. Cystic endometrial hyperplasia/pyometra complex in canine and feline endocrinology and reproduction. In: Feldman EC, Nelson RW. eds. Canine and Feline Endocrinology and Reproduction. 3^rd ed. St. Louis, Missouri: W.B. Saunders Company; 2004: 847-860
• 22 England GC, Freeman SL, Russo M. Treatment of spontaneous pyometra in 22 bitches with a combination of cabergoline and cloprostenol. Vet Rec 2007; 160 (09) 293-296
• 23 Sridevi P, Balasubramanian S, Devanathan TG. et al. Low dose prostaglandin F2 alpha therapy in treatment of canine pyometra. Indian Vet J 2000; 77 (10) 889-890
• 24 Verstegen J, Dhaliwal G, Verstegen-Onclin K. Mucometra, cystic endometrial hyperplasia, and pyometra in the bitch: advances in treatment and assessment of future reproductive success. Theriogenology 2008; 70 (03) 364-374
• 25 Arnold S, Hubler M, Casal M. et al. Use of low dose prostaglandin for the treatment of canine pyometra. J Small Anim Pract 1988; 29: 303-308
• 26 Davidson AP, Feldman EC, Nelson RW. Treatment of pyometra in cats, using prostaglandin F2 alpha: 21 cases (1982–1990). J Am Vet Med Assoc 1992; 200: 825-828
• 27 Garcia Mitacek MC, Stornelli MC, Tittarelli CM. et al. Cloprostenol treatment of feline open-cervix pyometra. J Feline Med Surg 2014; 16 (02) 177-179
• 28 Meyers-Wallen VN, Goldschmidt MH, Flickinger GL. Prostaglandin F2 alpha treatment of canine pyometra. J Am Vet Med Assoc 1986; 189 (12) 1557-1561
• 29 Gobello C, Castex G, Klima L. et al. A study of two protocols combining aglepristone and cloprostenol to treat open cervix pyometra in the bitch. Theriogenology 2003; 60 (05) 901-908
• 30 Onclin K, Verstegen JP. Practical use of a combination of a dopamine agonist and a synthetic prostaglandin analogue to terminate unwanted pregnancy in dogs. J Small Anim Pract 1996; 37 (05) 211-216
• 31 Corrada Y, Arias D, Rodriguez R. et al. Combination dopamine agonist and prostaglandin agonist treatment of cystic endometrial hyperplasia-pyometra complex in the bitch. Theriogenology 2006; 66 (6 – 7): 1557-1559
• 32 Hubler M, Arnold S, Casal M. et al. Use of low dose prostaglandin F2 alpha in bitches. Schweiz Arch Tierheilkd 1991; 133 (07) 323-329