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Exp Clin Endocrinol Diabetes 2019; 127(S 01): S93-S96
DOI: 10.1055/a-0984-5753
German Diabetes Association: Clinical Practice Guidelines
© Georg Thieme Verlag KG Stuttgart · New York

Diabetes and Fatty Liver

Norbert Stefan
1   German Center for Diabetes Research (DZD), Germany
2   Heisenberg Professorship and Chair of Clinical Experimental Diabetology, Department of Internal Medicine IV, Endocrinology, Diabetology, and Nephrology, University Hospital, Tübingen, Germany
3   Department of Pathophysiology of Prediabetes of the Institute for Diabetes Research and Metabolic Diseases (IDM) of Helmholtz Centre Munich, at the University of Tübingen, Germany
,
Michael Roden
1   German Center for Diabetes Research (DZD), Germany
4   Division for Endocrinology and Diabetology, Medical Faculty of the Heinrich Heine University and University Clinics, Düsseldorf, Germany
5   Institute for Clinical Diabetology, German Diabetes Center (DDZ), Leibniz Center for Diabetes Research and Heinrich Heine University, Düsseldorf, Germany
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Publication Date:
20 December 2019 (online)

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Nonalcoholic fatty liver disease (NAFLD) affects more than 25% of the adult population worldwide. According to analyses for 2016, Germany ranks third behind Greece (41%) and Italy (25.4%) in the prevalence of NAFLD (22.9% of the total population). An increase in the prevalence of NAFLD to 26.4% has been calculated for Germany (2.3) for the year 2030. At around 70%, the frequency of NAFLD is particularly high in people with obesity and/or type 2 diabetes [2]. However, NAFLD also occurs in about 7% of lean people and is then primarily of genetic origin [2]. In Europe and the USA, NAFLD is now regarded as the most frequent cause of chronic liver diseases although most people with NAFLD die from secondary diseases resulting from diabetes or cardiovascular diseases. Therefore, it is particularly important to test patients with type 2 diabetes for the presence, and especially the degree of severity, of NAFLD, and to plan therapy accordingly [3] [4].

 

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