Subscribe to RSS
DOI: 10.1055/a-0989-2791
Recommendations for Diagnosis and Treatment of Odontoid Fractures in Geriatric Patients
Article in several languages: English | deutschAbstract
Background Odontoid fractures in geriatric patients represent an entity of increasing incidence with a high rate of morbidity and mortality. The optimal diagnostic and therapeutic management is being controversially discussed in the literature.
Methods In a consensus process and based on the current literature, the members of the working groups “Osteoporotic Fractures” and “Upper Cervical Spine” of the German Society for Orthopaedics and Trauma Surgery (DGOU) defined recommendations for the diagnostics and treatment of odontoid fractures in geriatric patients.
Results For the diagnosis of odontoid fractures in symptomatic patients, computed tomography represents the gold standard, along with conventional radiographs. Magnetic resonance and dynamic imaging can be used as ancillary imaging modalities. With regard to fracture classification, the systems described by Anderson/DʼAlonzo and by Eysel/Roosen have proved to be of value. A treatment algorithm was developed based on these classifications. Anderson/DʼAlonzo type 1, type 3, and non-displaced type 2 fractures usually can be treated non-operatively. However, a close clinical and radiological follow-up is essential. In Anderson/DʼAlonzo type 2 fractures, operative treatment is associated with better fracture healing. Displaced type 2 and type 3 fractures should be stabilized operatively. Type 2 fractures with suitable fracture patterns (Eysel/Roosen 2A/B) can be stabilized anteriorly. Posterior C I/II-stabilization procedures are well established and suitable for all fracture patterns.
Publication History
Article published online:
21 October 2019
© 2019. Thieme. All rights reserved.
Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany
-
References/Literatur
- 1 Goldberg W, Mueller C, Panacek E. et al. Distribution and patterns of blunt traumatic cervical spine injury. Ann Emerg Med 2001; 38: 17-21 doi:10.1067/mem.2001.116150
- 2 Josten C, Jarvers JS, Glasmacher S. et al. Odontoid fractures in combination with C1 fractures in the elderly treated by combined anterior odontoid and transarticular C1/2 screw fixation. Arch Orthop Trauma Surg 2018; 138: 1525-1531 doi:10.1007/s00402-018-3013-y
- 3 Ryan MD, Henderson JJ. The epidemiology of fractures and fracture-dislocations of the cervical spine. Injury 1992; 23: 38-40
- 4 Hasler RM, Exadaktylos AK, Bouamra O. et al. Epidemiology and predictors of cervical spine injury in adult major trauma patients. A multicenter cohort study. J Trauma Acute Care Surg 2012; 72: 975-981 doi:10.1097/TA.0b013e31823f5e8e
- 5 Chapman J, Smith JS, Kopjar B. et al. The AOSpine North America Geriatric Odontoid Fracture Mortality Study: a retrospective review of mortality outcomes for operative versus nonoperative treatment of 322 patients with long-term follow-up. Spine (Phila Pa 1976) 2013; 38: 1098-1104 doi:10.1097/BRS.0b013e318286f0cf
- 6 Vaccaro AR, Kepler CK, Kopjar B. et al. Functional and quality-of-life outcomes in geriatric patients with type-II dens fracture. J Bone Joint Surg Am 2013; 95: 729-735 doi:10.2106/JBJS.K.01636
- 7 Venkatesan M, Northover JR, Wild JB. et al. Survival analysis of elderly patients with a fracture of the odontoid peg. Bone Joint J 2014; 96-B: 88-93 doi:10.1302/0301-620X.96B1.32024
- 8 Pal D, Sell P, Grevitt M. Type II odontoid fractures in the elderly: an evidence-based narrative review of management. Eur Spine J 2011; 20: 195-204 doi:10.1007/s00586-010-1507-6
- 9 Lewkonia P, Dipaola C, Schouten R. et al. An evidence-based medicine process to determine outcomes after cervical spine trauma. What surgeons should be telling their patients. Spine (Phila Pa 1976) 2012; 37: E1140-E1147 doi:10.1097/BRS.0b013e31825b2c10
- 10 Sasso RC. C2 dens fractures: treatment options. J Spinal Disord 2001; 14: 455-463
- 11 Ulm AJ, Quiroga M, Russo A. et al. Normal anatomical variations of the V3 segment of the vertebral artery: surgical implications. J Neurosurg Spine 2010; 13: 451-460 doi:10.3171/2010.4.SPINE09824
- 12 Wakao N, Takeuchi M, Nishimura M. et al. Risks for vascular injury during anterior cervical spine surgery. Prevalence of a medial loop of vertebral artery and internal carotid artery. Spine (Phila Pa 1976) 2016; 41: 293-298 doi:10.1097/BRS.0000000000001241
- 13 Hoffman JR, Mower WR, Wolfson AB. et al. Validity of a set of clinical criteria to rule out injury to the cervical spine in patients with blunt trauma. National Emergency X-Radiography Utilization Study Group. N Engl J Med 2000; 343: 94-99 doi:10.1056/NEJM200007133430203
- 14 Stiell IG, Wells GA, Vandemheen KL. et al. The Canadian C-spine rule for radiography in alert and stable trauma patients. JAMA 2001; 286: 1841-1848
- 15 Leidel BA, Kanz K-G, Mutschler W. Evidenzbasiertes diagnostisches Vorgehen bei Verdacht auf stumpfes HWS-Trauma. Entwicklung eines Algorithmus. Unfallchirurg 2005; 108: 905-919 doi:10.1007/s00113-005-0968-2
- 16 Hiratzka JR, Yoo JU, Ko JW. et al. Traditional threshold for retropharyngeal soft-tissue swelling is poorly sensitive for the detection of cervical spine injury on computed tomography in adult trauma patients. Spine (Phila Pa 1976) 2013; 38: E211-E216 doi:10.1097/BRS.0b013e31827f0dc3
- 17 Harris JH, Burke JT, Ray RD. et al. Low (type III) odontoid fracture: a new radiographic sign. Radiology 1984; 153: 353-356 doi:10.1148/radiology.153.2.6484166
- 18 Inaba K, Byerly S, Bush LD. et al. Cervical spinal clearance: a prospective Western Trauma Association Multi-institutional Trial. J Trauma Acute Care Surg 2016; 81: 1122-1130 doi:10.1097/TA.0000000000001194
- 19 Anderson LD, DʼAlonzo RT. Fractures of the odontoid process of the axis. J Bone Joint Surg Am 1974; 56: 1663-1674
- 20 Eysel P, Roosen K. Ventrale oder dorsale Spondylodese der Densbasisfraktur – eine neue Klassifikation zur Wahl des chirurgischen Zuganges. Zentralbl Neurochir 1993; 54: 159-165
- 21 Grauer JN, Shafi B, Hilibrand AS. et al. Proposal of a modified, treatment-oriented classification of odontoid fractures. Spine J 2005; 5: 123-129 doi:10.1016/j.spinee.2004.09.014
- 22 Benzel EC, Hart BL, Ball PA. et al. Fractures of the C-2 vertebral body. J Neurosurg 1994; 81: 206-212 doi:10.3171/jns.1994.81.2.0206
- 23 Radovanovic I, Urquhart JC, Rasoulinejad P. et al. Patterns of C-2 fracture in the elderly: comparison of etiology, treatment, and mortality among specific fracture types. J Neurosurg Spine 2017; 27: 494-500 doi:10.3171/2017.3.SPINE161176
- 24 Josten C, Jarvers JS, Glasmacher S. et al. Anterior transarticular atlantoaxial screw fixation in combination with dens screw fixation for type II odontoid fractures with associated atlanto-odontoid osteoarthritis. Eur Spine J 2016; 25: 2210-2217 doi:10.1007/s00586-016-4493-5
- 25 Robinson AL, Möller A, Robinson Y. et al. C2 fracture subtypes, incidence, and treatment allocation change with age: a retrospective cohort study of 233 consecutive cases. Biomed Res Int 2017; 2017: 8321680 doi:10.1155/2017/8321680
- 26 Deng H, Yue JK, Upadhyayula PS. et al. Odontoid fractures in the octogenarian: a systematic review and meta-analysis. J Neurosurg Sci 2016; 60: 543-555
- 27 Evaniew N, Yarascavitch B, Madden K. et al. Atlantoaxial instability in acute odontoid fractures is associated with nonunion and mortality. Spine J 2015; 15: 910-917 doi:10.1016/j.spinee.2014.03.029
- 28 Faure A, Graillon T, Pesenti S. et al. Trends in the surgical management of odontoid fractures in patients above 75 years of age: retrospective study of 70 cases. Orthop Traumatol Surg Res 2017; 103: 1221-1228 doi:10.1016/j.otsr.2017.07.008
- 29 Nourbakhsh A, Shi R, Vannemreddy P. et al. Operative versus nonoperative management of acute odontoid Type II fractures: a meta-analysis. J Neurosurg Spine 2009; 11: 651-658 doi:10.3171/2009.7.SPINE0991
- 30 Robinson Y, Robinson AL, Olerud C. Systematic review on surgical and nonsurgical treatment of type II odontoid fractures in the elderly. Biomed Res Int 2014; 2014: 231948 doi:10.1155/2014/231948
- 31 Joestl J, Lang N, Bukaty A. et al. A comparison of anterior screw fixation and halo immobilisation of type II odontoid fractures in elderly patients at increased risk from anaesthesia. Bone Joint J 2016; 98-B: 1222-1226 doi:10.1302/0301-620X.98B9.35216
- 32 Stein G, Meyer C, Marlow L. et al. Typ-II-Densfrakturen des alten Menschen und therapiebedingte Mortalität. Konservative oder operative Behandlung. Unfallchirurg 2017; 120: 122-128 doi:10.1007/s00113-015-0057-0
- 33 Bajada S, Ved A, Dudhniwala AG. et al. Predictors of mortality following conservatively managed fractures of the odontoid in elderly patients. Bone Joint J 2017; 99-B: 116-121 doi:10.1302/0301-620X.99B1.37989
- 34 Müller EJ, Wick M, Russe O. et al. Management of odontoid fractures in the elderly. Eur Spine J 1999; 8: 360-365
- 35 Graffeo CS, Perry A, Puffer RC. et al. Deadly falls: operative versus nonoperative management of Type II odontoid process fracture in octogenarians. J Neurosurg Spine 2017; 26: 4-9 doi:10.3171/2016.3.SPINE151202
- 36 Dhall SS, Yue JK, Winkler EA. et al. Morbidity and mortality associated with surgery of traumatic C2 fractures in octogenarians. Neurosurgery 2017; 80: 854-862 doi:10.1093/neuros/nyw168
- 37 Koech F, Ackland HM, Varma DK. et al. Nonoperative management of type II odontoid fractures in the elderly. Spine (Phila Pa 1976) 2008; 33: 2881-2886 doi:10.1097/BRS.0b013e31818d5407
- 38 Ajani AE, Cooper DJ, Scheinkestel CD. et al. Optimal assessment of cervical spine trauma in critically ill patients: a prospective evaluation. Anaesth Intensive Care 1998; 26: 487-491
- 39 Wagner SC, Schroeder GD, Kepler CK. et al. Controversies in the management of geriatric odontoid fractures. J Orthop Trauma 2017; 31 (Suppl. 04) S44-S48 doi:10.1097/BOT.0000000000000948
- 40 Delcourt T, Begue T, Saintyves G. et al. Management of upper cervical spine fractures in elderly patients. Current trends and outcomes. Injury 2015; 46 (Suppl. 01) S24-S27 doi:10.1016/S0020-1383(15)70007-0
- 41 Gallie W. Fractures and dislocations of the cervical spine. Am J Surg 1939; 46: 495-499
- 42 Magerl F, Seemann P-S. Stable posterior Fusion of the Atlas and Axis by transarticular Screw Fixation. In: Kehr P, Weidner A. eds. Cervical Spine I. Vienna: Springer; 1986: 322-327
- 43 Blauth M, Richter M, Lange U. Transartikuläre Verschraubung C1/C2 bei atlanto-axialer Instabilität. Vergleich zwischen perkutanem und offenen Vorgehen. Orthopäde 1999; 28: 651-661 doi:10.1007/PL00003654
- 44 Alhashash M, Shousha M, Gendy H. et al. Percutaneous posterior transarticular atlantoaxial fixation for the treatment of odontoid fractures in the elderly: a prospective study. Spine (Phila Pa 1976) 2018; 43: 761-766 doi:10.1097/BRS.0000000000002417
- 45 Harms J, Melcher RP. Posterior C1–C2 fusion with polyaxial screw and rod fixation. Spine (Phila Pa 1976) 2001; 26: 2467-2471
- 46 Du JY, Aichmair A, Kueper J. et al. Biomechanical analysis of screw constructs for atlantoaxial fixation in cadavers: a systematic review and meta-analysis. J Neurosurgery Spine 2015; 22: 151-161 doi:10.3171/2014.10.SPINE13805
- 47 Richter M, Schmidt R, Claes L. et al. Posterior atlantoaxial fixation: biomechanical in vitro comparison of six different techniques. Spine (Phila Pa 1976) 2002; 27: 1724-1732
- 48 Diel P, Schnake KJ, Langheinrich A. et al. Dislozierte Doppelgewindeschrauben nach Densosteosynthese in Knöringer-Technik. Unfallchirurg 2014; 117: 179-181 doi:10.1007/s00113-013-2388-z
- 49 Waschke A, Berger-Roscher N, Kielstein H. et al. Cement augmented anterior odontoid screw fixation is biomechanically advantageous in osteoporotic patients with Anderson Type II fractures. J Spinal Disord Tech 2015; 28: E126-E132 doi:10.1097/BSD.0000000000000177
- 50 Waschke A, Ullrich B, Kalff R. et al. Cement-augmented anterior odontoid screw fixation for osteoporotic type II odontoid fractures in elderly patients: prospective evaluation of 11 patients. Eur Spine J 2016; 25: 115-121 doi:10.1007/s00586-015-4084-x
- 51 Patterson JT, Theologis AA, Sing D. et al. Anterior versus posterior approaches for odontoid fracture stabilization in patients older than 65 years: 30-day morbidity and mortality in a national database. Clin Spine Surg 2017; 30: E1033-E1038 doi:10.1097/BSD.0000000000000494
- 52 Sen MK, Steffen T, Beckman L. et al. Atlantoaxial fusion using anterior transarticular screw fixation of C1–C2: technical innovation and biomechanical study. Eur Spine J 2005; 14: 512-518 doi:10.1007/s00586-004-0823-0