Neurologie up2date, Inhaltsverzeichnis Neurologie up2date 2021; 04(03): 255-268DOI: 10.1055/a-1163-6472 Kopfschmerz und andere Schmerzsyndrome Trigeminoautonome Kopfschmerzen Steffen Nägel , Torsten Kraya Artikel empfehlen Abstract Artikel einzeln kaufen Alle Artikel dieser Rubrik Im Vergleich zur Migräne und zum Kopfschmerz vom Spannungstyp sind trigeminoautonome Kopfschmerzen (TAK) zwar selten, aber die erhebliche Beeinträchtigung und die nicht unerhebliche Prävalenz [1] (z. B. Clusterkopfschmerz 0,1 %) machen TAK zu wichtigen Diagnosen. Die korrekte Diagnosestellung erfolgt allerdings leider oft verzögert. Dieser Beitrag gibt einen Überblick über das diagnostische Vorgehen und die therapeutischen Möglichkeiten bei TAK. Volltext Referenzen Literatur 1 Headache Classification Committee of the International Headache Society (IHS). The International Classification of Headache Disorders. 3rd ed. Cephalalgia 2018; 38: 1-211 2 Goadsby PJ, Holland PR, Martins-Oliveira M. et al. Pathophysiology of Migraine: A Disorder of Sensory Processing. Physiol Rev 2017; 97: 553-622 3 Obermann M, Holle D, Nagel S. Functional neuroimaging in trigeminal autonomic cephalalgias. Ann Indian Acad Neurol 2018; 21: S51-S56 4 Edvardsson B. Symptomatic cluster headache: a review of 63 cases. Springerplus 2014; 3: 64 5 Favier I, van Vliet JA, Roon KI. et al. Trigeminal autonomic cephalgias due to structural lesions: a review of 31 cases. Arch Neurol 2007; 64: 25-31 6 Mitsikostas DD, Ashina M. EHF committee. et al. European headache federation consensus on technical investigation for primary headache disorders. J Headache Pain 2015; 17: 5 7 Fischera M, Marziniak M, Gralow I. et al. The incidence and prevalence of cluster headache: a meta-analysis of population-based studies. Cephalalgia 2008; 28: 614-618 8 Manzoni GC, Taga A, Russo M. et al. Age of onset of episodic and chronic cluster headache - a review of a large case series from a single headache centre. J Headache Pain 2016; 17: 44 9 Rozen TD, Fishman RS. Cluster headache in the United States of America: demographics, clinical characteristics, triggers, suicidality, and personal burden. Headache 2012; 52: 99-113 10 Govare A, Leroux E. Licit and Illicit Drug Use in Cluster Headache. Curr Pain Headache Rep 2014; 18: 413 11 Gaul C, Christmann N, Schröder D. et al. Differences in clinical characteristics and frequency of accompanying migraine features in episodic and chronic cluster headache. Cephalalgia 2012; 32: 571-577 12 Bahra A, May A, Goadsby PJ. Cluster headache: a prospective clinical study with diagnostic implications. Neurology 2002; 58: 354-361 13 Burish MJ, Rozen TD. Trigeminal Autonomic Cephalalgias. Neurol Clin 2019; 37: 847-869 14 Gaul C, Diener H-C, Silver N. et al. Non-invasive vagus nerve stimulation for PREVention and Acute treatment of chronic cluster headache (PREVA): A randomised controlled study. Cephalalgia 2016; 36: 534-546 15 Goadsby PJ, de Coo IF, Silver N. et al. Non-invasive vagus nerve stimulation for the acute treatment of episodic and chronic cluster headache: A randomized, double-blind, sham-controlled ACT2 study. Cephalalgia 2018; 38: 959-969 16 Goadsby PJ, Cohen AS, Matharu MS. Trigeminal autonomic cephalalgias: diagnosis and treatment. Curr Neurol Neurosci Rep 2007; 7: 117-125 17 Obermann M, Nägel S, Ose C. et al. Safety and efficacy of prednisone versus placebo in short-term prevention of episodic cluster headache: a multicentre, double-blind, randomised controlled trial. Lancet Neurol 2021; 20: 29-37 18 Leroux E, Ducros A. Occipital injections for trigemino-autonomic cephalalgias: evidence and uncertainties. Curr Pain Headache Rep 2013; 17: 325 19 Abdel-Maksoud MB, Nasr A, Abdul-Aziz A. Lithium treatment in cluster headache: review of literature. Eur J Psychiat 2009; 23: 53-60 20 Sostak P, Krause P, Förderreuther S. et al. Botulinum toxin type-A therapy in cluster headache: an open study. J Headache Pain 2007; 8: 236-241 21 Ruscheweyh R, Broessner G, Goßrau G. et al. Effect of calcitonin gene-related peptide (-receptor) antibodies in chronic cluster headache: Results from a retrospective case series support individual treatment attempts. Cephalalgia 2020; 40: 1574-1584 22 Giani L, Proietti Cecchini A, Leone M. Cluster headache and TACs: state of the art. Neurol Sci 2020; 41: 367-375 23 Boes CJ, Dodick DW. Refining the clinical spectrum of chronic paroxysmal hemicrania: a review of 74 patients. Headache 2002; 42: 699-708 24 Cittadini E, Matharu MS, Goadsby PJ. Paroxysmal hemicrania: a prospective clinical study of 31 cases. Brain 2008; 131: 1142-1155 25 Ramusino MC, Perini G, Antonaci F. et al. The Treatment of Trigeminal Autonomic Cephalalgias: An Overview. J Oral Facial Pain Headache 2019; 33: 89-104 26 Naegel S, Holle D, Obermann M. Structural imaging in cluster headache. Curr Pain Headache Rep 2014; 18: 415