Alt und depressiv oder dement? – Pseudodepression vs. Pseudodemenz

Ältere Menschen mit kognitiven Defiziten werden ohne detaillierte Untersuchung oft schnell als dement eingestuft. Dabei kann hinter den Symptomen auch eine ausgeprägte Depression stecken. Erschwerend kommt hinzu, dass psychische und kognitive Veränderungen miteinander wechselwirken oder sich gegenseitig bedingen. Ob nun eine depressive Pseudodemenz oder eine Pseudodepression vorliegt, ist daher nicht immer leicht zu beantworten.

Abstract

Many elderly patients suffer from both, depressive symptoms and cognitive deficits. Clinically, it oftentimes appears unclear whether the affective or the cognitive problems are primary or secondary. Modern molecular and imaging markers contribute to a more efficient distinction between depression and incipient dementia due to neurodegenerative, vascular, and other diseases. A careful history and clinical investigations are necessary to identify the underlying diseases, but they do not always offer sufficient therapeutic guidance. If in doubt, the condition should always be considered as potentially reversible and treated emphatically (but with age-appropriate caution).

Schlüsselwörter

Depression - Pseudodemenz - Demenz - Risikofaktor - Komplikationen

Key words

depression - dementia - pseudodementia - risk factor - complications

Publication History

Article published online:
29 March 2021

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