Rofo 2021; 193(03): 276-288
DOI: 10.1055/a-1244-2775
Heart

The International Radiomics Platform – An Initiative of the German and Austrian Radiological Societies – First Application Examples

Article in several languages: English | deutsch
Daniel Overhoff
1   Department of Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Germany
,
Peter Kohlmann
2   Fraunhofer Institute for Digital Medicine MEVIS, Bremen, Germany
,
Alex Frydrychowicz
3   Department of Radiology and Nuclear Medicine, University Hospital Schleswig-Holstein, Campus Lübeck, Germany
,
Sergios Gatidis
4   Department of Diagnostic and Interventional Radiology, University-Hospital Tübingen, Germany
,
Christian Loewe
5   Department of Radiology, Medical University of Vienna, Austria
,
Jan Moltz
2   Fraunhofer Institute for Digital Medicine MEVIS, Bremen, Germany
,
Jan-Martin Kuhnigk
2   Fraunhofer Institute for Digital Medicine MEVIS, Bremen, Germany
,
Matthias Gutberlet
6   Department of Diagnostic and Interventional Radiology, Leipzig Heart Centre University Hospital, Leipzig, Germany
,
H. Winter
7   Department of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany
,
Martin Völker
8   German Roentgen Society „Deutsche Röntgengesellschaft“, Berlin, Germany
,
Horst Hahn
2   Fraunhofer Institute for Digital Medicine MEVIS, Bremen, Germany
,
Stefan O. Schoenberg
1   Department of Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Germany
,
Vorstandskommission Radiomics und Big data:
,
Vorstand der Deutschen Röntgengesellschaft:
,
Präsidium der Österreichischen Röntgengesellschaft:
› Author Affiliations

Abstract

Purpose The DRG-ÖRG IRP (Deutsche Röntgengesellschaft-Österreichische Röntgengesellschaft international radiomics platform) represents a web-/cloud-based radiomics platform based on a public-private partnership. It offers the possibility of data sharing, annotation, validation and certification in the field of artificial intelligence, radiomics analysis, and integrated diagnostics. In a first proof-of-concept study, automated myocardial segmentation and automated myocardial late gadolinum enhancement (LGE) detection using radiomic image features will be evaluated for myocarditis data sets.

Materials and Methods The DRG-ÖRP IRP can be used to create quality-assured, structured image data in combination with clinical data and subsequent integrated data analysis and is characterized by the following performance criteria: Possibility of using multicentric networked data, automatically calculated quality parameters, processing of annotation tasks, contour recognition using conventional and artificial intelligence methods and the possibility of targeted integration of algorithms. In a first study, a neural network pre-trained using cardiac CINE data sets was evaluated for segmentation of PSIR data sets. In a second step, radiomic features were applied for segmental detection of LGE of the same data sets, which were provided multicenter via the IRP.

Results First results show the advantages (data transparency, reliability, broad involvement of all members, continuous evolution as well as validation and certification) of this platform-based approach. In the proof-of-concept study, the neural network demonstrated a Dice coefficient of 0.813 compared to the expert's segmentation of the myocardium. In the segment-based myocardial LGE detection, the AUC was 0.73 and 0.79 after exclusion of segments with uncertain annotation.

The evaluation and provision of the data takes place at the IRP, taking into account the FAT (fairness, accountability, transparency) and FAIR (findable, accessible, interoperable, reusable) criteria.

Conclusion It could be shown that the DRG-ÖRP IRP can be used as a crystallization point for the generation of further individual and joint projects. The execution of quantitative analyses with artificial intelligence methods is greatly facilitated by the platform approach of the DRG-ÖRP IRP, since pre-trained neural networks can be integrated and scientific groups can be networked.

In a first proof-of-concept study on automated segmentation of the myocardium and automated myocardial LGE detection, these advantages were successfully applied.

Our study shows that with the DRG-ÖRP IRP, strategic goals can be implemented in an interdisciplinary way, that concrete proof-of-concept examples can be demonstrated, and that a large number of individual and joint projects can be realized in a participatory way involving all groups.

Key Points:

  • The DRG-ÖRG IRP is a web/cloud-based radiomics platform based on a public-private partnership.

  • The DRG-ÖRG IRP can be used for the creation of quality-assured, structured image data in combination with clinical data and subsequent integrated data analysis.

  • First results show the applicability of left ventricular myocardial segmentation using a neural network and segment-based LGE detection using radiomic image features.

  • The DRG-ÖRG IRP offers the possibility of integrating pre-trained neural networks and networking of scientific groups.

Citation Format

  • Overhoff D, Kohlmann P, Frydrychowicz A et al. The International Radiomics Platform – An Initiative of the German and Austrian Radiological Societies. Fortschr Röntgenstr 2021; 193: 276 – 287



Publication History

Received: 02 June 2020

Accepted: 17 July 2020

Article published online:
26 November 2020

© 2020. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 
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