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DOI: 10.1055/a-1274-9256
Serosazysten am Uterus der Hündin – Fallbericht und Literaturübersicht zu kaninen Uteruszysten
Uterine serosal inclusion cysts in the dog – case report and literature review of canine uterine cysts
Zusammenfassung
Uterine Zysten bei Hündinnen werden in der Regel mit pathologischen Zuständen in Verbindung gebracht. Eine Ausnahme stellen Serosazysten dar. Diese dünnwandigen, singulär oder multipel auf der Oberfläche des Uterus entstehenden Zysten besitzen keine endokrine Aktivität oder Abhängigkeit. Daher verursachen sie i. d. R. keine klinischen Symptome und sind in ihrem Auftreten nicht zyklusassoziiert. Serosazysten kommen vor allem bei älteren, multiparen Hündinnen großer Rassen vor. Die Diagnose ist mittels transabdominaler Sonografie möglich. Da sich Serosazysten häufig an der Uterushornspitze befinden, lassen sie sich mitunter schwer von Ovarialzysten differenzieren. In diesem Bericht wird der Fall einer Zuchthündin mit multiplen uterinen Serosazysten vorgestellt, die während einer Sectio caesarea detektiert wurden. Die Konzentrationen von Östradiol 17β und Progesteron in der Zystenflüssigkeit entsprachen der Konzentration der Hormone im Blut bei einer Hündin in der Geburt. Die Konzentrationen von Gesamtkalzium, Zink, Kupfer und Eisen in der Zystenflüssigkeit lagen unterhalb der Referenzwerte im Blut von Hunden. Die Konzentrationen von Magnesium, Phosphor, Natrium und Kalium des Zysteninhalts entsprachen den Werten im Blut.
Abstract
In bitches, uterine cysts are usually associated with pathological conditions. Serosal inclusion cysts of the uterus represent an exception to this rule. These thin-walled cysts develop on the uterine surface and occur either as single or multiple cysts. The cysts lack endocrine activity and usually do not cause clinical symptoms. Their occurrence shows no association to the estrus cycle. Serosal inclusion cysts are mainly found in older multiparous bitches and large breeds are more often affected. Diagnosis of serosal inclusion cysts may be achieved by transabdominal sonography. Differentiation between uterine and ovarian serosal inclusion cysts is possibly challenging as serosal inclusion cysts are often located in the area of the tip of the uterine horn. This report presents the case of a breeding bitch with multiple uterine serosal inclusion cysts detected during caesarean section. The concentrations of estradiol 17β and progesterone in the cyst fluid corresponded to the blood concentrations of these hormones in a bitch during parturition. The concentrations of total calcium, zinc, copper, and iron in the cyst fluid were below the reference values in canine blood whereas the concentrations of magnesium, phosphorus, sodium, and potassium in the cyst fluid were comparable to pertaining blood levels.
Publication History
Received: 24 September 2020
Accepted: 30 October 2020
Article published online:
04 December 2020
© 2020. Thieme. All rights reserved.
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Literatur
- 1 Davidson P, Baker TW. Reproductive Ultrasound of the Bitch and Queen. Top Companion Anim M 2009; 24 (02) 55-63
- 2 Kennedy PC, Cullen JM, Edwards JF. Tumors of the genital system. In: Kennedy PC. ed. Histological Classification of Tumors of the Genital System of Domestic Animals. Washington, DC: Armed Forces Inst. of Pathology; 1998: 28-39
- 3 Schlafer DH, Gifford AT. Cystic endometrial hyperplasia, pseudo-placentational endometrial hyperplasia, and other cystic conditions of the canine and feline uterus. Theriogenology 2008; (70) 349-358
- 4 Dow C. The cystic hyperplasia-pyometra complex in the bitch. J Comp Pathol 1959; 69: 237-250
- 5 Schlafer DH. Diseases of the Canine Uterus. Reprod Dom Anim 2012; 42: 318-322
- 6 Schlafer DH, Foster RA. Female genital system. In: Maxie MG, Jubb KVF, Kennedy P. et al., ed. Pathology of Domestic Animals. 6th ed.. St. Louis: Elsevier; 2016: 340-387
- 7 Agnew DW, MacLachlan NJ. Tumors of the Genital Systems. In: Meuten DJ. ed. Tumors in Domestic Animals. 5th ed.. Ames: Wiley Blackwell; 2017: 697-706
- 8 Hewicker-Trautwein M. Uterus. In: Baumgärtner W. Hrsg. Pathohistologie für die Tiermedizin.. 2. Aufl.. Stuttgart: Enke; 2012: 242-245
- 9 Beineke A, Klopfleisch R. Reproduktionsorgane. In: Baumgärtner W, Gruber AD. Hrsg. Spezielle Pathologie für die Tiermedizin. 1. Aufl.. Stuttgart: Enke; 2015: 239
- 10 Kim HS, Kang SC, Zhang HS. et al. Uterine Adenomyosis in Beagle Dogs. Lab Anim Res 2010; 26 (02) 211-213
- 11 Newell-Fugate A, Lane E. Intrapartum uterine rupture with coincidental uterine adenomyosis in an African wild dog (Lycaon pictus). J Zoo Wildl Med 2009; 40 (04) 791-795
- 12 Stöcklin-Gautschi NM, Guscetti F, Reichler IM. et al. Identification of focal adenomyosis as a uterine lesion in two dogs. J Small Anim Pract 2001; 42 (08) 413-416
- 13 Tamada H, Kawate N, Inaba T. Adenomyosis with severe inflammation in the uterine cervix in a dog. Can Vet J 2005; 46 (04) 333-334
- 14 Walter Y, Borschenksy C, Alfaro A. et al. Adenomyosis beim Hund – Bericht über drei Fälle. Kleintierprax 2009; 54 (11) 634-638
- 15 Gelberg HB, McEntee K. Pathology of the Canine and Feline Uterine Tube. Vet Pathol 1986; 23 (06) 770-775
- 16 McEntee K. Reproductive pathology of domestic mammals. London: Academic Press; 1990: 173-174
- 17 Wehrend A. Gynäkologische Störungen und Erkrankungen. In: Bostedt H, Günzel-Apel A. Hrsg. Reproduktionsmedizin und Neonatologie von Hund und Katze. 1. Aufl.. Stuttgart: Schattauer; 2016: 89-97
- 18 Johnston SD, Kustritz MV, Olson PS. ed. Disorders of the canine Uterus and Uterine Tubes (Oviducts). In: Canine and Feline Theriogenology. Philadelphia: Saunders; 2001: 206-224
- 19 Arnold S, Hubler M, Hauser B. et al. Uterine serosal inclusion cysts in a bitch. J Small Anim Pract 1996; 37: 235-237
- 20 Lee JA, Kim IH, Jang DW. et al. Pyometra and Serosal Inclusion Cysts of the Uterus in a Bitch. J Vet Clin 2013; 30 (04) 305-309
- 21 Sathiamoorthy T, Rangasamy S, Arunmozhi N. et al. Uterine serosal inclusion cysts coupled with pyometra in a bitch. Indian J Anim Reprod 2014; 35 (01) 61
- 22 Johnston SD, Kustritz MV, Olson PS. ed. Disorders of the canine ovary. In: Canine and Feline Theriogenology. Philadelphia: Saunders; 2001: 193-205
- 23 Godfrey DR, Silkstone MA. Uterine serosal inclusion cysts in a cat. Vet Rec 1998; 142 (24) 673
- 24 Sevimli A, Ozenc E, Acar DB. Oviduct cyst observed together with a uterine serosal inclusion cyst in the Anatolian water buffalo – a case report. Acta Vet Brno 2012; 81: 235-237
- 25 Abedini M, Ghaedi E, Hadi A. et al. Zinc status and polycystic ovarian syndrome: A systematic review and meta-analysis. J Trace Elem Med Biol 2019; 52: 216-221
- 26 Hoffmann B, Höveler R, Nohr B. et al. Investigations on hormonal changes around parturition in the dog and the occurrence of pregnancy-specific non conjugated oestrogens. Exp Clin Endocrinol 1994; 102: 185-189
- 27 Kaiser S. Uterine serosal inclusion cysts in a bitch. Kleintierprax 1978; 23: 397
- 28 Sathiamoorthy T, Raja S. Uterine serosal inclusion cysts in a bitch. Indian Vet J 2012; 89 (12) 89-90
- 29 Athira VP, Sudheesh. Nair S. et al. Panmetritis, endometrial hyperplasia and uterine serosal inclusion cyst in a bitch – a case report. Indian Vet J 2019; 96 (06) 52-53
- 30 Huisinga E. Elektrolyte. In: Moritz A. Hrsg. Klinische Labordiagnostik in der Tiermedizin. 7. Aufl.. Stuttgart: Schattauer; 2013: 336-354