Recent Progress in the Gold-Catalyzed Annulations of Ynamides with Isoxazole Derivatives via α-Imino Gold Carbenes

Abstract

During the past two decades, gold-catalyzed nitrene-transfer reactions via α-imino gold carbenes have received extensive attention, as this strategy provides rapid access to nitrogen-containing molecules with high efficiency. In this review, we focus on recent progress in gold-catalyzed formal annulations of ynamides with isoxazole derivatives as nitrene-transfer reagents via α-imino gold carbenes in atom-economic and rapid construction of N-heterocycles.

Key words

gold catalysis - gold carbenes - ynamides - isoxazoles - annulations - N-heterocycles

Publication History

Received: 13 November 2020

Accepted after revision: 02 January 2021

Accepted Manuscript online:
02 January 2021

Article published online:
05 February 2021

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