No Influence of Nonivamide-nicoboxil on the Peak Power Output in Competitive Sportsmen

Theresa Schörkmaier; Yvonne Wahl; Christian Brinkmann; Wilhelm Bloch; Patrick Wahl

doi:10.1055/a-1403-2701

International Journal of Sports Medicine, Inhaltsverzeichnis

CC BY-NC-ND 4.0 · Int J Sports Med 2021; 42(12): 1092-1097
DOI: 10.1055/a-1403-2701

Physiology & Biochemistry

No Influence of Nonivamide-nicoboxil on the Peak Power Output in Competitive Sportsmen

Autoren

Theresa Schörkmaier

¹Department of Clinical Research, German Centre for Neurodegenerative Diseases, Bonn, Germany
Yvonne Wahl

⁵Insitute of Exercise Training and Sport Informatics, German Sport University Cologne, Cologne, Germany
Christian Brinkmann

³Department of Preventive and Rehabilitative Sport Medicine, Institute of Cardiovascular Research and Sport Medicine, German Sport University Cologne, Cologne, Germany
Wilhelm Bloch

²The German Research Centre of Elite Sport, German Sport University Cologne, Cologne, Germany

⁴Department of Molecular and Cellular Sport Medicine, Institute of Cardiology and Sports Medicine, German Sport University Cologne, Cologne, Germany
Patrick Wahl

²The German Research Centre of Elite Sport, German Sport University Cologne, Cologne, Germany

⁴Department of Molecular and Cellular Sport Medicine, Institute of Cardiology and Sports Medicine, German Sport University Cologne, Cologne, Germany

⁶Institute of Interdisciplinary Exercise Science and Sports Medicine, Medical School Hamburg, Germany

Abstract

Recent studies have shown that the oxygenated hemoglobin level can be enhanced during rest through the application of nonivamide-nicoboxil cream. However, the effect of nonivamide-nicoboxil cream on oxygenation and endurance performance under hypoxic conditions is unknown. Therefore, the purpose of this study was to investigate the effects of nonivamide-nicoboxil cream on local muscle oxygenation and endurance performance under normoxic and hypoxic conditions. In a cross-over design, 13 athletes (experienced cyclists or triathletes [age: 25.2±3.5 years; VO₂max 62.1±7.3 mL·min⁻¹·kg⁻¹]) performed four incremental exercise tests on the cycle ergometer under normoxic or hypoxic conditions, either with nonivamide-nicoboxil or placebo cream. Muscle oxygenation was recorded with near-infrared spectroscopy. Capillary blood samples were taken after each step, and spirometric data were recorded continuously. The application of nonivamide-nicoboxil cream increased muscle oxygenation at rest and during different submaximal workloads as well as during physical exhaustion, irrespective of normoxic or hypoxic conditions. Overall, there were no significant effects of nonivamide-nicoboxil on peak power output, maximal oxygen uptake or lactate concentrations. Muscle oxygenation is significantly higher with the application of nonivamide-nicoboxil cream. However, its application does not increase endurance performance.

Key words

muscle oxygenation - near-infrared spectroscopy (NIRS) - cycling - hypoxia

Volltext

Referenzen

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