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Synlett 2021; 32(10): 1039-1043
DOI: 10.1055/a-1479-6005
DOI: 10.1055/a-1479-6005
letter
Synthesis of [6,6,m]-Tricyclic Compounds via [4+2] Cycloaddition with Au or Cu Catalyst
This work was supported by a grant from the National Research Foundation of Korea (NRF), funded by the Korean Government, through the Center for New Directions in Organic Synthesis (NRF-2021R1A5A6002803).
Abstract
We synthesized [6,6,6]- and [6,6,7]-tricyclic compounds via intramolecular [4+2] cycloaddition by gold or copper catalysts. Substrates for cyclization were prepared by coupling reactions between eight types of diyne and four types of aromatic moieties. We have successfully synthesized eleven tricyclic compounds.
Key words
catalysis - [4+2] cycloaddition - abietane - Dendrobium - [6,6,m]-cyclic compound - copper - goldSupporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/a-1479-6005.
- Supporting Information
Publication History
Received: 21 March 2021
Accepted after revision: 11 April 2021
Accepted Manuscript online:
11 April 2021
Article published online:
23 April 2021
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