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CC BY-NC-ND 4.0 · Geburtshilfe Frauenheilkd 2021; 81(06): 637-653
DOI: 10.1055/a-1483-2782
GebFra Science
Review/Übersicht

Treatment of Patients with Early Breast Cancer: Evidence, Controversies, Consensus

German Expert Opinions on the 17th International St. Gallen Consensus Conference Article in several languages: English | deutsch
Michael Untch   *
1   Klinik für Gynäkologie und Geburtshilfe, interdisziplinäres Brustzentrum, HELIOS Klinikum Berlin Buch, Berlin, Germany
,
Peter A. Fasching   *
2   Frauenklinik des Universitätsklinikums Erlangen, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
,
Sara Y. Brucker   **   #
3   Universitäts-Frauenklinik Tübingen, Tübingen, Germany
,
Wilfried Budach   **
4   Klinik für Strahlentherapie und Radioonkologie, Universitätsklinik Düsseldorf, Düsseldorf, Germany
,
Carsten Denkert   **   #
5   Pathologisches Institut, Philipps Universität Marburg und Universitätsklinikum Marburg (UKGM), Marburg, Germany
,
Renate Haidinger   *
6   Brustkrebs Deutschland e. V., Hohenbrunn, Germany
,
Jens Huober   *   #
7   Brustzentrum Kantonsspital St. Gallen, St. Gallen, Switzerland
8   Brustzentrum, Universitätsfrauenklinik Ulm, Ulm, Germany
,
Christian Jackisch   *
9   Klinik für Gynäkologie und Geburtshilfe, Sana-Klinikum Offenbach GmbH, Offenbach, Germany
,
Wolfgang Janni   *
10   Universitätsfrauenklinik Ulm, Ulm, Germany
,
Cornelia Kolberg-Liedtke   *
11   Klinik für Frauenheilkunde und Geburtshilfe, Universitätsklinikum Essen, Essen, Germany
12   palleos healthcare GmbH, Wiesbaden, Germany
13   Phaon scientific GmbH, Wiesbaden, Germany
,
David Krug   *
14   Klinik für Strahlentherapie (Radioonkologie), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Kiel, Germany
,
Thorsten Kühn   *
15   Klinik für Frauenheilkunde und Geburtshilfe, Klinikum Esslingen, Esslingen, Germany
,
Sibylle Loibl   **   #
16   German Breast Group (GBG), Neu-Isenburg, Germany
17   Centrum für Hämatologie und Onkologie Bethanien, Frankfurt am Main, Germany
,
Diana Lüftner   *
18   Medizinische Klinik mit Schwerpunkt Hämatologie, Onkologie und Tumorimmunologie, Charité Campus Virchow-Klinikum, Berlin, Germany
,
Volkmar Müller   **
19   Klinik und Poliklinik für Gynäkologie, Universitätsklinik Hamburg-Eppendorf (UKE), Hamburg, Germany
,
Andreas Schneeweiss   *
20   Sektionsleiter Gynäkologische Onkologie, Nationales Centrum für Tumorerkrankungen (NCT) Universitätsklinikum Heidelberg, Heidelberg, Germany
21   Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany
,
Marc Thill   *
22   Klinik für Gynäkologie und Gynäkologische Onkologie, Interdisziplinäres Brustzentrum, Agaplesion Markus Krankenhaus, Frankfurt am Main, Germany
,
Nadia Harbeck   *   #
23   Brustzentrum, Frauenklinik, LMU Klinikum, München, Germany
,
Christoph Thomssen   *
24   Universitätsklinik und Poliklinik für Gynäkologie, Martin-Luther-Universität Halle-Wittenberg, Halle (Saale), Germany
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Abstract

This yearʼs 17th St. Gallen (SG) Consensus Conference on the Treatment of Patients with Early Breast Cancer (SG-BCC) with the title “Customizing local and systemic therapies for women with early breast cancer” focused on the challenge of targeting the treatment of early breast cancer more specifically to the individual disease situation of each patient. As in previous years, a German working group of leading breast cancer experts discussed the results of the international SG-BCC 2021 in the context of the German guideline. It is helpful to compare the SG recommendations with the recently updated treatment recommendations of the Breast Commission of the German Working Group on Gynaecological Oncology (Arbeitsgemeinschaft Gynäkologische Onkologie e. V., AGO) and the S3 guideline because the SG-BCC panel comprised experts from different countries, which is why country-specific aspects can be incorporated into the SG recommendations. The German treatment recommendations of the AGO and the S3 guideline are based on current evidence. Nevertheless, any therapeutic decision must always undergo a risk-benefit analysis for the specific situation and to be discussed with the patient.

Key words

St. Gallen Consensus 2021 - early breast cancer - surgery - radiotherapy - (neo)adjuvant systemic therapy - targeted therapy

* Writing Committee


** Steering Committee


# St. Gallen Panel Expert




Publication History

Received: 08 April 2021

Accepted after revision: 20 April 2021

Article published online:
19 May 2021

© 2021. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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