Synthesis of Cyclic Phosphinates by Microwave-Assisted Ionic-Liquid-Promoted Alcoholysis

Nikoletta Harsági; Nóra Zsuzsa Kiss; László Drahos; György Keglevich

doi:10.1055/a-1504-8924

Synthesis, Table of Contents

Synthesis 2022; 54(17): 3899-3905
DOI: 10.1055/a-1504-8924

special topic

Special Issue in memory of Prof. Ferenc Fülöp

Synthesis of Cyclic Phosphinates by Microwave-Assisted Ionic-Liquid-Promoted Alcoholysis

Nikoletta Harsági

^aDepartment of Organic Chemistry and Technology, Budapest University of Technology and Economics, 1521 Budapest, Hungary

,

Nóra Zsuzsa Kiss

^aDepartment of Organic Chemistry and Technology, Budapest University of Technology and Economics, 1521 Budapest, Hungary

,

László Drahos

^bResearch Centre for Natural Sciences, MS Proteomics Research Group, 1117 Budapest, Hungary

,

György Keglevich∗

^aDepartment of Organic Chemistry and Technology, Budapest University of Technology and Economics, 1521 Budapest, Hungary

› Author Affiliations

Abstract

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Dedicated to Professor Ferenc Fülöp on the occasion of his 70^th birthday

Abstract

A series of 1-alkoxy-3-methyl- and 3,4-dimethyl-3-phospholene 1-oxides, as well as 1-alkoxy-3-methylphospholane 1-oxides were prepared in good yields by the microwave (MW)-assisted [bmim][PF₆]-catalyzed transesterification of the corresponding methyl or ethyl esters. The alcoholyses studied represent another case, where MW irradiation has had a crucial role on the course of the reaction. The method developed is an alternative possibility to other esterifications starting from the corresponding phosphinic chlorides and acids.

Key words

alcoholysis - transesterification - phospholene oxide - phospholane oxide - microwave - ionic liquid

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References

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