Neurologie up2date, Table of Contents Neurologie up2date 2023; 06(02): 165-178DOI: 10.1055/a-1527-3322 Immunvermittelte und erregerbedingte Erkrankungen des ZNS Progressive multifokale Leukenzephalopathie: Diagnostik und Therapieoptionen Lea Grote-Levi , Nora Möhn , Mike P. Wattjes , Thomas Skripuletz Recommend Article Abstract Buy Article All articles of this category Das humane Polyomavirus 2 kann insbesondere bei immunkompromittierten Personen eine potenziell lebensgefährliche zerebrale opportunistische Infektion, die progressive multifokale Leukenzephalopathie (PML), auslösen. Bisher steht keine zugelassene wirksame kausale Therapie zur Verfügung. Dieser Beitrag zeigt, wie die Erkrankung diagnostiziert werden kann und welche aktuellen experimentellen Therapiemaßnahmen erfolgversprechend sind. Full Text References Literatur 1 Tan CS, Koralnik IJ. Progressive multifocal leukoencephalopathy and other disorders caused by JC virus: clinical features and pathogenesis. 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