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Sprache · Stimme · Gehör 2021; 45(04): 185-189
DOI: 10.1055/a-1557-8414
Schwerpunktthema

Sprechmotorische Störungen bei primär progredienter Aphasie

Motor Speech Disorders in Primary Progressive Aphasia
Anja Staiger
,
Wolfram Ziegler
,
Matthias L. Schroeter
,
Janine Diehl-Schmid
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Primär progrediente Aphasien (PPA) können mit Störungen der Sprechmotorik (Sprechapraxie, Dysarthrie) einhergehen. In diesem Artikel wird der aktuelle Wissensstand zu den Auftretenshäufigkeiten und Formen sprechmotorischer Störungen bei allen Subtypen der PPA referiert.

Abstract

Primary progressive aphasia (PPA) may be associated with motor speech disorders (apraxia of speech, dysarthria). In this article, we review the current knowledge on the frequency of occurrence and the forms of motor speech disorders in all subtypes of PPA.

Schlüsselwörter

Primär progrediente Aphasie (PPA) - sprechmotorische Störungen - Dysarthrie - Sprechapraxie

Keywords

Primary progressive aphasia (PPA) - motor speech disorders - dysarthria - apraxia of speech


Publication History

Article published online:
30 November 2021

© 2021. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

  • Literatur

  • 1 Mesulam M. Primary progressive aphasia. Ann Neurol 2001; 49: 425-432
    CrossrefPubMedGoogle Scholar
  • 2 Gorno-Tempini M, Hillis A, Weintraub S. et al. Classification of primary progressive aphasia and its variants. Neurology 2011; 76: 1006-1014
    CrossrefPubMedGoogle Scholar
  • 3 Lashley T, Rohrer JD, Mead S. et al. An update on clinical, genetic and pathological aspects of frontotemporal lobar degenerations. Neuropathol Appl Neurobiol 2015; 41: 858-881
    CrossrefPubMedGoogle Scholar
  • 4 Duffy JR, Strand EA, Josephs KA. Motor speech disorders associated with primary progressive aphasia. Aphasiology 2014; 28: 1004-1017
    CrossrefPubMedGoogle Scholar
  • 5 Ziegler W, Staiger A. Motor speech impairments. Hickock G, Small S. The neurobiology of Language. Waltham, MA: Academic Press; 2016: 985-994
    Google Scholar
  • 6 Ziegler W, Aichert I, Staiger A. Sprechapraxie: Grundlagen, Diagnostik, Therapie. Heidelberg: Springer; 2020
    CrossrefGoogle Scholar
  • 7 Duffy JR, Utianski RL, Josephs KA. Primary progressive apraxia of speech: from recognition to diagnosis and care. Aphasiology 2020; 1-32
    PubMedGoogle Scholar
  • 8 Cordella C, Quimby M, Touroutoglou A. et al. Quantification of motor speech impairment and its anatomic basis in primary progressive aphasia. Neurology 2019; 92: e1992-e2004
    CrossrefPubMedGoogle Scholar
  • 9 Staiger A, Schroeter ML, Ziegler W. et al. Motor speech disorders in the nonfluent, semantic and logopenic variants of primary progressive aphasia. Cortex 2021; 140: 66-79
    CrossrefPubMedGoogle Scholar
  • 10 Duffy JR. Motor Speech Disorders: Substrates, Differential Diagnosis, and Management. 4th Aufl. St. Louis, MO: Elsevier; 2020
    Google Scholar
  • 11 Takakura Y, Otsuki M, Sakai S. et al. Sub-classification of apraxia of speech in patients with cerebrovascular and neurodegenerative diseases. Brain and Cognition 2019; 130: 1-10
    CrossrefPubMedGoogle Scholar
  • 12 Josephs KA, Duffy JR, Strand EA. et al. Syndromes dominated by apraxia of speech show distinct characteristics from agrammatic PPA. Neurology 2013; 81: 337-345
    CrossrefPubMedGoogle Scholar
  • 13 Botha H, Josephs KA. Primary progressive aphasias and apraxia of speech. Continuum: Lifelong Learning in Neurology 2019; 25: 101-127
    CrossrefPubMedGoogle Scholar
  • 14 Poole ML, Brodtmann A, Darby D. et al. Motor speech phenotypes of frontotemporal dementia, primary progressive aphasia, and progressive apraxia of speech. J Speech Lang Hear Res 2017; 60: 897-911
    CrossrefPubMedGoogle Scholar
  • 15 Ogar JM, Dronkers NF, Brambati SM. et al. Progressive nonfluent aphasia and its characteristic motor speech deficits. Alzheimer Diseas Assoc Disord 2007; 21: S23-S30
    CrossrefPubMedGoogle Scholar
  • 16 Santos-Santos MA, Mandelli ML, Binney RJ. et al. Features of Patients With Nonfluent/Agrammatic Primary Progressive Aphasia With Underlying Progressive Supranuclear Palsy Pathology or Corticobasal Degeneration. JAMA Neurol 2016; 73: 733-742
    CrossrefPubMedGoogle Scholar
  • 17 Tan RH, Guennewig B, Dobson-Stone C. et al. The underacknowledged PPA-ALS: A unique clinicopathologic subtype with strong heritability. Neurology 2019; 92: e1354-e1366
    CrossrefPubMedGoogle Scholar
  • 18 Croot K, Ballard KJ, Leyton CE. et al. Apraxia of speech and phonological errors in the diagnosis of nonfluent/agrammatic and logopenic variants of primary progressive aphasia. J Speech Lang Hear Res 2012; 55: S1562-S1572
    CrossrefPubMedGoogle Scholar
  • 19 Duncan ES, Donovan NJ, Sajjadi SA. Clinical Assessment of Characteristics of Apraxia of Speech in Primary Progressive Aphasia. Am J Speech-Lang Pathol 2020; 29: 485-497
    CrossrefPubMedGoogle Scholar
  • 20 Matías-Guiu JA, Cabrera-Martín MN, Moreno-Ramos T. et al. Amyloid and FDG-PET study of logopenic primary progressive aphasia: evidence for the existence of two subtypes. J Neurol 2015; 262: 1463-1472
    CrossrefPubMedGoogle Scholar