HMPA-Free Generation of Trialkylsilyllithium Reagents and Its Applications to the Synthesis of Silylboronic Esters

Abstract

Trialkylsilyllithium species have turned out to be facilely generated by treating hexaalkyldisilanes with methyllithium in the presence of tris(N,N-tetramethylene)phosphoric triamide (TPPA) as an activator, which can be trapped by boron electrophiles to afford silylboronic esters including long-awaited Me₃Si–B(pin).

Key words

trialkylsilyllithium - hexaalkyldisilane - silylboronic ester - TPPA­ - HMPA

Publikationsverlauf

Eingereicht: 08. Juli 2021

Angenommen nach Revision: 26. Juli 2021

Accepted Manuscript online:
26. Juli 2021

Artikel online veröffentlicht:
23. August 2021

• References


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