Download PDF
Klin Monbl Augenheilkd 2021; 238(09): 951-961
DOI: 10.1055/a-1562-8731
Übersicht

Moderne bildgebende Verfahren zur Darstellung der Morphologie und Funktion der Aderhaut

Article in several languages: English | deutsch
Marion Munk
Universitätsklinik für Augenheilkunde, Inselspital Universitätsspital Bern, Schweiz
,
Chantal Dysli
Universitätsklinik für Augenheilkunde, Inselspital Universitätsspital Bern, Schweiz
› Author Affiliations
› Further Information
Also available at
    Permissions and Reprints

Zusammenfassung

Die Aderhaut oder Choroidea liegt direkt außerhalb der Netzhaut an und besteht aus einem dichten Gefäßnetz, das die äußere Netzhaut versorgt. Pathologien im Bereich der Aderhaut können zu Veränderungen des retinalen Pigmentepithels (RPE) und der äußeren Netzhautschichten führen. Die Aderhaut spielt somit eine entscheidende Rolle bei der Entstehung von Netzhauterkrankungen wie der altersabhängigen Makuladegeneration (AMD), der Chorioretinopathia centralis serosa (CRCS, CSCR, RCS), der pathologischen Myopie und bei inflammatorischen Erkrankungen wie dem Vogt-Koyanagi-Harada-Syndrom (VKH). Die grundlegende Kenntnis des Aufbaus und der Physiologie der Aderhaut sowie der diagnostischen Optionen zur Darstellung von choroidalen Veränderungen ermöglicht ein besseres Verständnis der Physiologie und Pathologie choroidaler Prozesse. Diese Arbeit bietet einen Überblick der Anatomie und Funktion der Choroidea und beschreibt die aktuell verfügbaren diagnostischen Verfahren zur Charakterisierung und Darstellung der Aderhaut. Anschließend werden verschiedene Krankheitsbilder, die mit choroidalen Veränderungen assoziiert sind, beleuchtet.

Schlüsselwörter

Choroidea - Choriokapillaris - okuläre Bildgebung - Choroidopathie - chorioretinale Pathologie


Publication History

Received: 06 July 2021

Accepted: 30 July 2021

Article published online:
07 September 2021

© 2021. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

  • References/Literatur

  • 1 Nickla DL, Wallman J. The multifunctional choroid. Prog Retin Eye Res 2010; 29: 144-168
    CrossrefPubMedSearch in Google Scholar
  • 2 Ramrattan RS, van der Schaft TL, Mooy CM. et al. Morphometric analysis of Bruchʼs membrane, the choriocapillaris, and the choroid in aging. Invest Ophthalmol Vis Sci 1994; 35: 2857-2864
    PubMedSearch in Google Scholar
  • 3 Zhao J, Wang YX, Zhang Q. et al. Macular Choroidal Small-Vessel Layer, Sattlerʼs Layer and Hallerʼs Layer Thicknesses: The Beijing Eye Study. Sci Rep 2018; 8: 4411
    CrossrefPubMedSearch in Google Scholar
  • 4 Pichi F, Aggarwal K, Neri P. et al. Choroidal biomarkers. Indian J Ophthalmol 2018; 66: 1716-1726
    CrossrefPubMedSearch in Google Scholar
  • 5 Alm A, Nilsson SF. Uveoscleral outflow–a review. Exp Eye Res 2009; 88: 760-768
    CrossrefPubMedSearch in Google Scholar
  • 6 Kinoshita T, Mitamura Y, Shinomiya K. et al. Diurnal variations in luminal and stromal areas of choroid in normal eyes. Br J Ophthalmol 2017; 101: 360-364
    CrossrefPubMedSearch in Google Scholar
  • 7 Sarfare S, Yang J, Nickla DL. The effects of brief high intensity light on ocular growth in chicks developing myopia vary with time of day. Exp Eye Res 2020; 195: 108039
    CrossrefPubMedSearch in Google Scholar
  • 8 Mrejen S, Spaide RF. Imaging the choroid in uveitis. Int Ophthalmol Clin 2012; 52: 67-81
    CrossrefPubMedSearch in Google Scholar
  • 9 Invernizzi A, Pellegrini M, Cornish E. et al. Imaging the Choroid: From Indocyanine Green Angiography to Optical Coherence Tomography Angiography. Asia Pac J Ophthalmol (Phila) 2020; 9: 335-348
    CrossrefPubMedSearch in Google Scholar
  • 10 Godel V, Baruch E, Lazar M. Late development of chorioretinal lesions in birdshot retinochoroidopathy. Ann Ophthalmol 1989; 21: 49-52
    PubMedSearch in Google Scholar
  • 11 Shah KH, Levinson RD, Yu F. et al. Birdshot chorioretinopathy. Surv Ophthalmol 2005; 50: 519-541
    CrossrefPubMedSearch in Google Scholar
  • 12 Soubrane G, Bokobza R, Coscas G. Late developing lesions in birdshot retinochoroidopathy. Am J Ophthalmol 1990; 109: 204-210
    CrossrefPubMedSearch in Google Scholar
  • 13 Copete S, Flores-Moreno I, Montero JA. et al. Direct comparison of spectral-domain and swept-source OCT in the measurement of choroidal thickness in normal eyes. Br J Ophthalmol 2014; 98: 334-338
    CrossrefPubMedSearch in Google Scholar
  • 14 Chee SP, Chan SN, Jap A. Comparison of Enhanced Depth Imaging and Swept Source Optical Coherence Tomography in Assessment of Choroidal Thickness in Vogt-Koyanagi-Harada Disease. Ocul Immunol Inflamm 2017; 25: 528-532
    CrossrefPubMedSearch in Google Scholar
  • 15 Gal-Or O, Dansingani KK, Sebrow D. et al. Inner Choroidal Flow Signal Attenuation in Pachychoroid Disease: Optical Coherence Tomography Angiography. Retina 2018; 38: 1984-1992
    CrossrefPubMedSearch in Google Scholar
  • 16 Siedlecki J, Schworm B, Priglinger SG. The Pachychoroid Disease Spectrum-and the Need for a Uniform Classification System. Ophthalmol Retina 2019; 3: 1013-1015
    CrossrefPubMedSearch in Google Scholar
  • 17 Munk MR, Shah R, Pappas F. et al. Multimodal Imaging and Choroidal Volumetric Changes After Half-fluence PDT in Central Serous Chorioretinopathy. Curr Eye Res 2016; 41: 97-106
    CrossrefPubMedSearch in Google Scholar
  • 18 Romdhane K, Mantel I. Choroidal Neovascularisation Complicating Chronic Central Serous Chorioretinopathy: The Discovery Rate on Multimodal Imaging. Klin Monbl Augenheilkd 2019; 236: 536-541
    Thieme ConnectPubMedSearch in Google Scholar
  • 19 [Anonym] Argon laser photocoagulation for neovascular maculopathy. Three-year results from randomized clinical trials. Macular Photocoagulation Study Group. Arch Ophthal 1986; 104: 694-701
    CrossrefPubMedSearch in Google Scholar
  • 20 [Anonym] Laser photocoagulation for juxtafoveal choroidal neovascularization. Five-year results from randomized clinical trials. Macular Photocoagulation Study Group. Arch Ophthal 1994; 112: 500-509
    CrossrefPubMedSearch in Google Scholar
  • 21 [Anonym] Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin: one-year results of 2 randomized clinical trials–TAP report. Treatment of age-related macular degeneration with photodynamic therapy (TAP) Study Group. Arch Ophthal 1999; 117: 1329-1345
    CrossrefPubMedSearch in Google Scholar
  • 22 Spaide RF, Jaffe GJ, Sarraf D. et al. Consensus Nomenclature for Reporting Neovascular Age-Related Macular Degeneration Data: Consensus on Neovascular Age-Related Macular Degeneration Nomenclature Study Group. Ophthalmology 2020; 127: 616-636
    CrossrefPubMedSearch in Google Scholar
  • 23 Sadda SR, Guymer R, Holz FG. et al. Consensus Definition for Atrophy Associated with Age-Related Macular Degeneration on OCT: Classification of Atrophy Report 3. Ophthalmology 2018; 125: 537-548
    CrossrefPubMedSearch in Google Scholar
  • 24 Gaucher D, Sebah C, Erginay A. et al. Optical coherence tomography features during the evolution of serous retinal detachment in patients with diabetic macular edema. Am J Ophthalmol 2008; 145: 289-296
    CrossrefPubMedSearch in Google Scholar
  • 25 Munk MR, Bolz M, Huf W. et al. Morphologic and functional evaluations during development, resolution, and relapse of uveitis-associated cystoid macular edema. Retina 2013; 33: 1673-1683
    CrossrefPubMedSearch in Google Scholar
  • 26 Giocanti-Auregan A, Hrarat L, Qu LM. et al. Functional and Anatomical Outcomes in Patients With Serous Retinal Detachment in Diabetic Macular Edema Treated With Ranibizumab. Invest Ophthalmol Vis Sci 2017; 58: 797-800
    CrossrefPubMedSearch in Google Scholar