Abstract
Electrochemistry has recently gained increased attention as a versatile strategy for achieving challenging transformations at the forefront of synthetic organic chemistry. However, most electrochemical transformations only employ one electrode (anodic oxidation or cathodic reduction) to afford the desired products, while the chemistry that occurs at the counter electrode yields stoichiometric waste. In contrast, paired electrochemical reactions can synchronously utilize the anodic and cathodic reactions to deliver the desired product, thus improving the atom economy and energy efficiency of the electrolytic process. This review gives an overview of recent advances in nickel-catalyzed paired electrochemical cross-coupling reactions of aryl/alkenyl halides with different nucleophiles.
1 Introduction
2 Nickel-Catalyzed Cross-Coupling Reactions
2.1 C–C Bond Formation
2.2 C–N Bond Formation
2.3 C–S/O Bond Formation
2.4 C–P Bond Formation
3 Conclusion
Key words
electrochemistry - paired electrolysis - nickel catalysis - cross-coupling - redox neutral reactions
