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CC BY 4.0 · TH Open 2021; 05(03): e411-e414
DOI: 10.1055/a-1585-9536
Letter to the Editor

Thrombembolic Events in Hospitalized COVID-19 Patients: What is the Role of the Sex?

Irit Nachtigall
1   Helios Kliniken Ost and Klinikum Emil-von-Behring, Berlin, Germany
2   Heart Center Leipzig at University of Leipzig and Leipzig Heart Institute, Leipzig Germany
,
Sven Hohenstein
2   Heart Center Leipzig at University of Leipzig and Leipzig Heart Institute, Leipzig Germany
,
Andreas Bollmann
2   Heart Center Leipzig at University of Leipzig and Leipzig Heart Institute, Leipzig Germany
,
Marzia Bonsignore
3   Evangelische Kliniken Gelsenkirchen, Zentrum für Krankenhaushygiene und Infektiologie, Gelsenkirchen, Germany
,
Daniela Husser
2   Heart Center Leipzig at University of Leipzig and Leipzig Heart Institute, Leipzig Germany
,
Ralf Kuhlen
4   Helios Health, Berlin, Germany
,
Andreas Meier Hellmann
5   Helios Kliniken GmbH, Berlin, Germany
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Over a year ago, the WHO declared COVID-19 a pandemic; from then on, all hopes were on the development of vaccines. So far, 4 vaccines have been approved in Europe. On March 11th, 2021, the European Medicines Agency (EMA) reported ∼30 cases of thromboembolic events (TE) that were observed within 2 weeks after vaccinations with the AstraZeneca vaccine Vaxzevria, mostly being cerebral venous sinus thromboses in women younger than 60 years. Ca. 5 million people had received Vaxzevria in the EEA by then. Several European countries stopped their vaccinations with Vaxzevria temporarily.

COVID-19 infections increase the risk of developing TE. It has not yet been reported whether women develop more TE under Covid-19 than men. The aim of the present study was to determine the frequency, sex distribution and risk factors of TE among SARS-CoV-2 positive patients.



Publication History

Accepted Manuscript online:
12 August 2021

Article published online:
21 September 2021

© 2021. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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