Transition-Metal-Catalyzed Stereo- and Regioselective Hydrosilylation of Unsymmetrical Alkynes

Dedicated to the 100^th Anniversary of Chemistry at Nankai University.

Abstract

Alkyne hydrosilylation is one of the most efficient methods for the synthesis of alkenyl silicon derivatives and has been a hot topic of research for decades. This short review summarizes the progress in transition-metal-catalyzed stereo- and regioselective hydrosilylation of unsymmetrical alkynes. Topics are discussed based on different types of alkynes and the selectivities.

1 Introduction

2 Terminal Alkyne Hydrosilylation

2.1 β-E Selectivity

2.2 β-Z Selectivity

2.3 α-selectivity

3 Internal Alkyne Hydrosilylation

3.1 Aryl–Alkyl Acetylenes

3.2 Alkyl–Alkyl Acetylenes

3.3 Internal Alkynes with Polarized Substituents

4 Summary and Outlook

Key words

hydrosilylation - transition-metal catalysts - alkynes - alkenyl silicons - selectivity

Publication History

Received: 07 July 2021

Accepted after revision: 23 August 2021

Accepted Manuscript online:
23 August 2021

Article published online:
14 October 2021

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