Synthesis, Table of Contents Synthesis 2022; 54(02): 475-482DOI: 10.1055/a-1645-6040 paper Synthesis of Aryl Dithiocarbamates from Tetramethylthiuram Monosulfide (TMTM) and Aryl Boronic Acids: Copper-Catalyzed Construction of C(sp2)–S Bonds Xu-Ling Xia‡ a School of Chemistry and Environmental Engineering, Wuhan Institute of Technology, Wuhan 430205, P. R. of China , Qi-Long Zhu‡ a School of Chemistry and Environmental Engineering, Wuhan Institute of Technology, Wuhan 430205, P. R. of China , Jin-Quan Chen a School of Chemistry and Environmental Engineering, Wuhan Institute of Technology, Wuhan 430205, P. R. of China , Zhen Shi b Hubei Key Laboratory of Biologic Resources Protection and Utilization, Hubei Minzu University, Enshi 445000, P. R. of China , Zhi-Bing Dong ∗ a School of Chemistry and Environmental Engineering, Wuhan Institute of Technology, Wuhan 430205, P. R. of China b Hubei Key Laboratory of Biologic Resources Protection and Utilization, Hubei Minzu University, Enshi 445000, P. R. of China c School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang 453007, P. R. of China d Key Laboratory of Green Chemical Process, Ministry of Education, Wuhan Institute of Technology, Wuhan 430205, P. R. of China › Author Affiliations Recommend Article Abstract Buy Article All articles of this category Abstract A highly efficient method for the synthesis of S-aryl dithiocarbamates is reported. By using tetramethylthiuram monosulfide (TMTM) and aryl boronic acids as starting materials, C(sp2)–S bond-forming reactions proceed smoothly to give the desired aryl dithiocarbamates in good to excellent yields. The methodology features a simple procedure, broad functional group tolerance and excellent yields, whilst showing potential synthetic value for the preparation of a diverse range of biologically and pharmaceutically active compounds. Key words Key wordsdithiocarbamates - tetramethylthiuram monosulfide - boronic acids - organosulfur - copper Full Text References References 1a Ilardi EA, Vitaku E, Njardarson JT. J. Med. Chem. 2014; 57: 283 1b Liu X, Dong ZB. Eur. J. Org. Chem. 2020; 408 1c Peng K, Zhu H, Liu X, Peng HY, Chen JQ, Dong ZB. Eur. J. Org. Chem. 2019; 7629 1d Peng K, Dong ZB. Adv. Synth. Catal. 2021; 363: 1 1e Chen JQ, Li JH, Dong ZB. Adv. Synth. Catal. 2020; 16: 3311 1f Peng K, Dong ZB. Eur. J. Org. Chem. 2020; 5488 1g Wu XM, Yan GB. Synlett 2019; 30: 610 1h Miyaura N, Suzuki A. Chem. Rev. 1995; 95: 2457 1i Suzuki A. J. Organomet. Chem. 1999; 576: 147 1j Wu ZM, Li YC, Ding WZ, Zhu T, Liu SZ, Ren XH, Zou LH. Asian J. Org. 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