CC BY-NC-ND 4.0 · Ultrasound Int Open 2021; 07(02): E48-E54
DOI: 10.1055/a-1652-1261
Original Article

Transthoracic Vector Flow Imaging in Pediatric Patients with Valvular Stenosis – A Proof of Concept Study

Tin-Quoc Nguyen
1   Department of Diagnostic Radiology, Rigshospitalet Diagnostisk Center, Copenhagen, Denmark
2   Department of Clinical Medicine, University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen, Denmark
,
3   Department of Radiology, Odense University Hospital, Odense, Denmark
,
Michael Rahbek Schmidt
4   Rigshospitalet Hjertecentret, The Heart Center, Copenhagen, Denmark
,
Klaus Juul
5   Department of Pediatric Cardiology, Rigshospitalet, Copenhagen, Denmark
,
Ramin Moshavegh
6   BK Medical ApS, Herlev, Denmark
,
Lars Lönn
1   Department of Diagnostic Radiology, Rigshospitalet Diagnostisk Center, Copenhagen, Denmark
2   Department of Clinical Medicine, University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen, Denmark
,
1   Department of Diagnostic Radiology, Rigshospitalet Diagnostisk Center, Copenhagen, Denmark
2   Department of Clinical Medicine, University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen, Denmark
,
Jørgen Arendt Jensen
7   Department of Health Technology, Technical University of Denmark, Kgs. Lyngby, Denmark
,
Kristoffer Lindskov Hansen
1   Department of Diagnostic Radiology, Rigshospitalet Diagnostisk Center, Copenhagen, Denmark
2   Department of Clinical Medicine, University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen, Denmark
› Institutsangaben

Abstract

Purpose Continuous wave Doppler ultrasound is routinely used to detect cardiac valve stenoses. Vector flow imaging (VFI) is an angle-independent real-time ultrasound method that can quantify flow complexity. We aimed to evaluate if quantification of flow complexity could reliably assess valvular stenosis in pediatric patients.

Materials and Methods Nine pediatric patients with echocardiographically confirmed valvular stenosis were included in the study. VFI and Doppler measurements were compared with transvalvular peak-to-peak pressure differences derived from invasive endovascular catheterization.

Results Vector concentration correlated with the catheter measurements before intervention after exclusion of one outlier (r=−0.83, p=0.01), whereas the Doppler method did not (r=0.49, p=0.22). The change in vector concentration after intervention correlated strongly with the change in the measured catheter pressure difference (r=−0.86, p=0.003), while Doppler showed a tendency for a moderate correlation (r=0.63, p=0.07).

Conclusion Transthoracic flow complexity quantification calculated from VFI data is feasible and may be useful for assessing valvular stenosis severity in pediatric patients.



Publikationsverlauf

Eingereicht: 17. Dezember 2020

Angenommen nach Revision: 05. September 2021

Artikel online veröffentlicht:
17. November 2021

© 2021. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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