CC BY 4.0 · Synthesis 2022; 54(03): 517-534
DOI: 10.1055/a-1657-2634
review

The Rise of Manganese-Catalyzed Reduction Reactions

a   Max Planck Institute for Chemical Energy Conversion, Stiftstr. 34–36, 45470 Mülheim an der Ruhr, Germany
b   Institut für Technische und Makromolekulare Chemie (ITMC), RWTH Aachen University, Worringer Weg 2, 52074 Aachen, Germany
,
a   Max Planck Institute for Chemical Energy Conversion, Stiftstr. 34–36, 45470 Mülheim an der Ruhr, Germany
c   Ruhr University Bochum, Universitätsstr. 150, 44801 Bochum, Germany
› Author Affiliations
We gratefully acknowledge the Max-Planck-Gesellschaft (Max Planck Society) for financial support.


Abstract

Recent developments in manganese-catalyzed reducing transformations—hydrosilylation, hydroboration, hydrogenation, and transfer hydrogenation—are reviewed herein. Over the past half a decade (i.e., 2016 to the present), more than 115 research publications have been reported in these fields. Novel organometallic compounds and new reduction transformations have been discovered and further developed. Significant challenges that had historically acted as barriers for the use of manganese catalysts in reduction reactions are slowly being broken down. This review will hopefully assist in developing this research area, by presenting a clear and concise overview of the catalyst structures and substrate transformations published so far.

1 Introduction

2 Hydrosilylation

3 Hydroboration

4 Hydrogenation

5 Transfer Hydrogenation

6 Conclusion and Perspective



Publication History

Received: 17 August 2021

Accepted after revision: 09 September 2021

Accepted Manuscript online:
29 September 2021

Article published online:
24 November 2021

© 2021. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by/4.0/)

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