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Dtsch Med Wochenschr 2022; 147(13): 831-840
DOI: 10.1055/a-1685-6919
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Körperliche Aktivität bei Krebs – Wirksamkeit bewegungstherapeutischer Ansätze

Physical activity in cancer – effectiveness of exercise therapy approaches
Stefanie Siebert
,
Jane Kersten
,
Sebastian Theurich
,
Freerk T. Baumann
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Körperliche Aktivität bei Krebs – Wirksamkeit bewegungstherapeutischer AnsätzeDtsch Med Wochenschr 2022; 147(13): e1-e1
DOI: 10.1055/a-1894-2962

Bewegungstherapie in individualisierter Form bei onkologischen Patienten ist vor, während und auch nach Abschluss der medizinischen Therapie machbar und sicher und kann Nebenwirkungen, wie beispielsweise dem Fatigue-Syndrom oder der Polyneuropathie entgegenwirken. Dieser Beitrag gibt einen Überblick über die aktuellen bewegungstherapeutischen Ansätze bei onkologischen Patienten.

Abstract

The positive effects of oncological exercise therapy are sufficiently proven according to scientific studies. International evidence-based guidelines confirm this importance and recommend physical exercise as part of the standard therapy for cancer. The effects of physical activity on cancer-specific deficits are versatile ranging from positive impact on fatigue syndrome, mortality, incontinence, lymphoedema, CIPN, anxiety, depression to reduction of pain. According to current knowledge, sensorimotor training is recommended for the treatment of polyneuropathy. The actual effectiveness of vibration training in reducing symptom burden is undetermined. There are more than 100 randomized, controlled studies with the highest evidence rating for the management of CrF available. In this regard, exercise therapy is more effective than drug therapy in alleviating the symptomatology of CrF. In addition to the movement-therapeutic approach, a coordinated diet is necessary to avoid nutrition shortages.

The evidence on physical activity in oncology must be considered not only in theory, but also in practice and be accepted as a general recommendation for oncology patients. The personalized OTT treatment concept represents a practical implementation and offers a targeted treatment option with low side effects.

Schlüsselwörter

Bewegung - Krebs - Fatigue - Polyneuropathie - onkologische Trainings- und Bewegungstherapie - OTT

Key words

physical activity - cancer - personalized exercise concept - fatigue - polyneuropathy


Publication History

Article published online:
04 July 2022

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  • Literatur

  • 1 Robert Koch-Institut und die Gesellschaft der epidemiologischen Krebsregister in Deutschland e.V., Hrsg. Krebs in Deutschland für 2017/2018. Berlin: Robert Koch-Institut; 2021. Im Internet (Stand: 02.05.2022): https://edoc.rki.de/bitstream/handle/176904/9042/krebs_in_deutschland_2021.pdf%3Bjsessionid%3D3B7086E853920E599859A5232A68DFA9.pdf?sequence=1&isAllowed=y
    PubMed
  • 2 Kron F, Hallek M. Wissen generierende Versorgung in der Onkologie. Forum 2018; 33: 345-350
    CrossrefPubMedSearch in Google Scholar
  • 3 Schink K, Herrmann HJ, Schwappacher R. et al. Effects of whole-body electromyostimulation combined with individualized nutritional support on body composition in patients with advanced cancer: a controlled pilot trial. BMC Cancer 2018; 18: 886
    CrossrefPubMedSearch in Google Scholar
  • 4 Ibrahim EM, Al-Homaidh A. Physical activity and survival after breast cancer diagnosis: meta-analysis of published studies. Med Oncol 2011; 28: 753-765
    CrossrefPubMedSearch in Google Scholar
  • 5 Schmid D, Leitzmann MF. Association between physical activity and mortality among breast cancer and colorectal cancer survivors: a systematic review and meta-analysis. Ann Oncol 2014; 25: 1293-1311
    CrossrefPubMedSearch in Google Scholar
  • 6 Schmidt T, Hermes A, Weisser B. Physical Training Influences the Immune System of Breast Cancer Patients. Dtsch Z Sportmed 2017; 2017: 53-60
    CrossrefPubMedSearch in Google Scholar
  • 7 Fairey AS, Courneya KS, Field CJ. et al. Effect of exercise training on C-reactive protein in postmenopausal breast cancer survivors: a randomized controlled trial. Brain Behav Immun 2005; 19: 381-388
    CrossrefPubMedSearch in Google Scholar
  • 8 Peters C, Lötzerich H, Niemeir B. et al. Exercise, cancer and the immune response of monocytes. Anticancer Res 1995; 15: 175-179
    PubMedSearch in Google Scholar
  • 9 Steindorf K, Schmidt M, Zimmer P. Sport und Bewegung mit und nach Krebs – wer profitiert, was ist gesichert?. DZO 2019; 51: 21-26
    Thieme ConnectPubMedSearch in Google Scholar
  • 10 Dimeo FC, Thomas F, Raabe-Menssen C. et al Effect of aerobic exercise and relaxation training on fatigue and physical performance of cancer patients after surgery. A randomised controlled trial. Support Care Cancer 2004; 12: 774-779
    CrossrefPubMedSearch in Google Scholar
  • 11 Wu HS, Harden JK. Symptom burden and quality of life in survivorship: a review of the literature. Cancer Nurs 2015; 38: E29-E54
    CrossrefPubMedSearch in Google Scholar
  • 12 Cormie P, Zopf EM, Zhang X. et al. The Impact of Exercise on Cancer Mortality, Recurrence, and Treatment-Related Adverse Effects. Epidemiol Rev 2017; 39: 71-92
    CrossrefPubMedSearch in Google Scholar
  • 13 Fearon KCH, Glass DJ, Guttridge DC. Cancer cachexia: mediators, signaling, and metabolic pathways. Cell Metab 2012; 16: 153-166
    CrossrefPubMedSearch in Google Scholar
  • 14 Andreyev HJN, Norman AR, Oates J. et al. Why do patients with weight loss have a worse outcome when undergoing chemotherapy for gastrointestinal malignancies?. Eur J Cancer 1998; 34: 503-509
    CrossrefPubMedSearch in Google Scholar
  • 15 Aapro M, Arends J, Bozzetti F. et al. Early recognition of malnutrition and cachexia in the cancer patient: a position paper of a European School of Oncology Task Force. Ann Oncol 2014; 25: 1492-1499
    CrossrefPubMedSearch in Google Scholar
  • 16 Christensen JF, Simonsen C, Hojman P. Exercise Training in Cancer Control and Treatment. Compr Physiol 2018; 9: 165-205
    CrossrefPubMedSearch in Google Scholar
  • 17 Schmitz KH, Campbell AM, Stuiver MM. et al. Exercise is medicine in oncology: Engaging clinicians to help patients move through cancer. CA Cancer J Clin 2019; 69: 468-484
    CrossrefPubMedSearch in Google Scholar
  • 18 Treanor C, Kyaw T, Donnelly M. An international review and meta-analysis of prehabilitation compared to usual care for cancer patients. J Cancer Surviv 2018; 12: 64-73
    CrossrefPubMedSearch in Google Scholar
  • 19 Kirkham AA, Gelmon KA, van Patten CL. et al. Impact of Exercise on Chemotherapy Tolerance and Survival in Early-Stage Breast Cancer: A Nonrandomized Controlled Trial. J Natl Compr Canc Netw 2020; 18: 1670-1677
    CrossrefPubMedSearch in Google Scholar
  • 20 Niels T, Schürhörster A, Wirtz P. et al. Die Onkologische Trainings- und Bewegungstherapie (OTT). Bewegungsther Gesundheitssport 2018; 34: 50-54
    Thieme ConnectPubMedSearch in Google Scholar
  • 21 Rueffer JU. Fatigue – ein unterschätztes Problem. In: Petermann-Meyer A, Panse J, Brümmendorf TH. Hrsg. Leben mit Krebs. Berlin: Springer; 2021: 125-132
    Search in Google Scholar
  • 22 Wayne PM, Lee MS, Novakowski J. et al. Tai Chi and Qigong for cancer-related symptoms and quality of life: a systematic review and meta-analysis. J Cancer Surviv 2018; 12: 256-267
    CrossrefPubMedSearch in Google Scholar
  • 23 Larkey LK, Roe DJ, Weihs KL. et al. Randomized controlled trial of Qigong/Tai Chi Easy on cancer-related fatigue in breast cancer survivors. Ann Behav Med 2015; 49: 165-176
    CrossrefPubMedSearch in Google Scholar
  • 24 Hilfiker R, Meichtry A, Eicher M. et al. Exercise and other non-pharmaceutical interventions for cancer-related fatigue in patients during or after cancer treatment: a systematic review incorporating an indirect-comparisons meta-analysis. Br J Sports Med 2018; 52: 651-658
    CrossrefPubMedSearch in Google Scholar
  • 25 Mols F, Beijers T, Vreugdenhil G. et al. Chemotherapy-induced peripheral neuropathy and its association with quality of life: a systematic review. Support Care Cancer 2014; 22: 2261-2269
    CrossrefPubMedSearch in Google Scholar
  • 26 Soveri LM, Lamminmäki A, Hänninen UA. et al. Long-term neuropathy and quality of life in colorectal cancer patients treated with oxaliplatin containing adjuvant chemotherapy. Acta Oncol 2019; 58: 398-406
    CrossrefPubMedSearch in Google Scholar
  • 27 Bennett BK, Park SB, Lin CSY. et al. Impact of oxaliplatin-induced neuropathy: a patient perspective. Support Care Cancer 2012; 20: 2959-2967
    CrossrefPubMedSearch in Google Scholar
  • 28 Kerckhove N, Collin A, Condé S. et al. Long-Term Effects, Pathophysiological Mechanisms, and Risk Factors of Chemotherapy-Induced Peripheral Neuropathies: A Comprehensive Literature Review. Front Pharmacol 2017; 8: 86
    CrossrefPubMedSearch in Google Scholar
  • 29 AWMF. Interdisziplinäre S3-Leitlinie für die Früherkennung, Diagnostik, Therapie und Nachsorge des Mammakarzinoms. AWMF-Registernr. 032-045OL; 2021. Im Internet (Stand: 02.05.2022): https://www.awmf.org/leitlinien/detail/ll/032-045OL.html
    PubMed
  • 30 Streckmann F, Zopf EM, Lehmann HC. et al. Exercise intervention studies in patients with peripheral neuropathy: a systematic review. Sports Med 2014; 44: 1289-1304
    CrossrefPubMedSearch in Google Scholar
  • 31 Wonders KY, Whisler G, Loy H. et al. Ten Weeks of Home-Based Exercise Attenuates Symptoms of Chemotherapy-Induced Peripheral Neuropathy in Breast Cancer Patients. Health Psychol Res 2013; 1: e28
    CrossrefPubMedSearch in Google Scholar
  • 32 Ritzmann R, Gollhofer A, Kramer A. The influence of vibration type, frequency, body position and additional load on the neuromuscular activity during whole body vibration. Eur J Appl Physiol 2013; 113: 1-11
    CrossrefPubMedSearch in Google Scholar
  • 33 Kordi Yoosefinejad A, Shadmehr A, Olyaei G. et al. Short-term effects of the whole-body vibration on the balance and muscle strength of type 2 diabetic patients with peripheral neuropathy: a quasi-randomized-controlled trial study. J Diabetes Metab Disord 2015; 14: 45
    CrossrefPubMedSearch in Google Scholar
  • 34 Paice JA, Shott S, Oldenburg PF. et al. Efficacy of a vibratory stimulus for the relief of HIV-associated neuropathic pain. Pain 2000; 84: 291-296
    CrossrefPubMedSearch in Google Scholar
  • 35 Wirtz P, Tomanek A, Baumann FT. Bedeutung von Sport und Bewegung für „cancer survivors“. Forum 2019; 34: 35-38
    CrossrefPubMedSearch in Google Scholar
  • 36 Baumann FT, Hallek M, Meyer J. et al. Onkologische Trainings- und Bewegungstherapie (OTT). Dtsch Med Wochenschr 2015; 140: 1457-1461
    Thieme ConnectPubMedSearch in Google Scholar