Zusammenfassung
Blepharitis ist eine häufige entzündliche Erkrankung der Augenlider einschließlich des Lidrandes, die bei Erwachsenen und Kindern auftreten und schwere Symptome hervorrufen haben kann. Je
nach anatomischer Lokalisation kann die Blepharitis in anteriore und posteriore Formen eingeteilt werden. Die Pathogenese der chronischen Blepharitis ist noch nicht vollständig geklärt, es
wird jedoch ein multifaktorielles Krankheitsgeschehen vermutet. Die Erkrankung stellt eine therapeutische Herausforderung dar.
Abstract
Blepharitis represents a frequent inflammatory condition of the lids including the lid margin, which can be apparent in adults and children. Chronic blepharitis is therapeutically
challenging. According to the anatomic localization, blepharitis can be graded in anterior and posterior forms. Blepharitis can lead to severe symptoms and complications, mainly dry eye
disease, corneal complications and defective lid position. The pathogenesis of chronic blepharitis is not fully understood so far, however, multifactorial disease proceedings are supposed,
which include systemic diseases (mainly dermatological disorders), habitual bacteria and infections. In all these processes inflammatory changes are the common final path.
Therapeutic strategies include topical and systemic therapies, however evidence levels are generally low and patients are often resistant to therapy. Basic therapeutic measures are warm
compresses, lid hygiene and lubricants. Topical anti-inflammatory drugs comprise corticosteroids and ciclosporin A. Topical and systemic antibiotics are commonly used. Systemic intake of
omega-3 fatty acids is often recommended due to its anti-inflammatory potential.
Schlüsselwörter
Blepharitis - Rosazea - anteriore Blepharitis - posteriore Blepharitis - Meibom-Drüsen-Dysfunktion
Key words
blepharitis - rosacea - anterior blepharitis - posterior blepharitis - meibomian gland dysfunction
