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Synlett 2022; 33(02): 177-181
DOI: 10.1055/a-1691-0449
DOI: 10.1055/a-1691-0449
letter
s-Tetrazine: Robust and Green Photoorganocatalyst for Aerobic Oxidation of N,N-Disubstituted Hydroxylamines to Nitrones
T.L. thanks the Université Paris-Saclay for the doctoral fellowships. JL thanks China Scholarship Council for the doctoral fellowship. P.A. thanks the Institut Universitaire de France for personal and financial support.
Abstract
Efficient photocatalytic aerobic oxidative dehydrogenation reactions of N,N-disubstituted hydroxylamines to nitrones were developed with an in situ generated photocatalyst based on commercially available 3,6-dichlorotetrazine. This process affords a wide range of nitrones in high yields under mild conditions. In addition, an oxidative (3+3) cycloaddition between an oxyallyl cation precursor and a hydroxylamine was also developed.
Supporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/a-1691-0449.
- Supporting Information
Publication History
Received: 12 October 2021
Accepted after revision: 09 November 2021
Accepted Manuscript online:
09 November 2021
Article published online:
23 November 2021
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