Osteoporose-Therapie: Compliance und Adhärenz in COVID-19 Zeiten

Zusammenfassung

Zu Beginn der COVID-19-Pandemie gab es keine Vorgaben von Fachgesellschaften oder Leitlinien hinsichtlich der Versorgung von Osteoporosepatient*innen. Die fortgesetzte Versorgung und die Behandlung beruhten auf lokalen Ad-hoc-Strategien. Inwiefern dies zu einer Verschlechterung der Versorgung von Osteoporosepatienten geführt hat, ist 18 Monate nach Ausbruch der Pandemie Thema aufkommender Publikationen. Dieser Artikel konzentriert sich auf das Thema Compliance und Adhärenz in der Osteoporosetherapie zu COVID-19 Zeiten mit den Fragen: Hat die COVID-19 Pandemie Einfluss genommen auf Patienten Compliance und Adhärenz? Welche Maßnahmen wurden ergriffen, die Versorgung von Patienten aufrecht zu erhalten und somit die Compliance zu beeinflussen? Welche Lehren sind für die Zukunft zu ziehen?

Abstract

At the onset of the COVID-19 pandemic, there was no guidance from professional societies or guidelines regarding the care of osteoporosis sufferers. Continued care and treatment was based on ad hoc local strategies. The extent to which this has led to a deterioration in the care of patients with osteoporosis is the subject of emerging publications 18 months after the outbreak of the pandemic. This article focuses on the issue of compliance and adherence to osteoporosis therapy at COVID-19 times with the questions: did the COVID-19 pandemic influence patient compliance and adherence? What measures were taken to maintain patient care? What lessons can be learned for the future?

Publication History

Received: 17 October 2021

Accepted: 19 November 2021

Article published online:
21 February 2022

• Literatur

• 1 GBD Disease and Injury Incidence and Prevalence Collaborators Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018;392:1789–1858
• 2 Secco GG. et al. “Decrease and delay in hospitalization for acute coronary syndromes during the 2020 SARS-CoV-2 pandemic”. Canadian Journal of Cardiology 36.7 (2020): 1152-1155
• 3 Gluckman TJ. et al. "Case rates, treatment approaches, and outcomes in acute myocardial infarction during the coronavirus disease 2019 pandemic." JAMA cardiology 5.12 (2020): 1419-1424
• 4 Morley J. et al. "Persistence and compliance with osteoporosis therapies among postmenopausal women in the UK Clinical Practice Research Datalink." Osteoporosis International 31.3 (2020): 533-545
• 5 Yap AF, Thirumoorthy T, Kwan YH. Systematic review of the barriers affecting medication adherence in older adults. Geriatrics & gerontology international 2016; 16: 1093-1101
• 6 Krendl AC, Perry BL. The impact of sheltering in place during the COVID-19 pandemic on older adults’ social and mental well-being. The Journals of Gerontology: Series B 2021; 76: e53-e58
• 7 Robbins R, Weaver MD, Czeisler MÉ, Barger LK, Quan SF, Czeisler CA. (2021). Associations between changes in daily behaviors and self-reported feelings of depression and anxiety about the COVID-19 pandemic among older adults. The Journals of Gerontology Series B: Psychological Sciences and Social Sciences
• 8 Benke C. et al. "Lockdown, quarantine measures, and social distancing: Associations with depression, anxiety and distress at the beginning of the COVID-19 pandemic among adults from Germany.". Psychiatry Research 2020; 293: 113462
• 9 Moßhammer D, Haumann H, Mörike K, Joos S. Polypharmacy – an upward trend with unpredictable effects. Dtsch Arztebl Int 2016; 113: 627-633 DOI: 10.3238/arztebl.2016.0627.
• 10 Rahman S. et al. "The double burden of the COVID-19 pandemic and polypharmacy on geriatric population – Public health implications.". Therapeutics and clinical risk management 2020; 16: 1007
• 11 Aggarwal P, Woolford SJ, Patel HP. Multi-morbidity and polypharmacy in older people: challenges and opportunities for clinical practice. Geriatrics 2020; 5: 85
• 12 Chandran M, Hao Y, Kwee AK, Cheen MHH, Chin YA, Ng VYT. (2021). Adherence to dosing schedule of denosumab therapy for osteoporosis during COVID-19 lockdown: an electronic medical record and pharmacy claims database study from Asia. Osteoporosis International, 1-11
• 13 Kocijan R, Behanova M, Reichardt B, Haschka J, Kocijan A, Zwerina J. Poor adherence to parenteral osteoporosis therapies during COVID-19 pandemic. Archives of Osteoporosis 2021; 16: 1-3
• 14 Peeters JJM, van den Berg P, van den Bergh JP, Emmelot-Vonk MH, de Klerk G, Lems WF, Appelman-Dijkstra NM. Osteoporosis care during the COVID-19 pandemic in the Netherlands: a national survey. Archives of Osteoporosis 2021; 16: 1-8
• 15 Pinelli E. et al. "Effects of COVID-19 Lockdown on Adherence to Individual Home-or Gym-Based Exercise Training among Women with Postmenopausal Osteoporosis." International Journal of Environmental Research and Public Health 18.5 (2021): 2441
• 16 Chaabene H, Prieske O, Herz M, Moran J, Höhne J, Kliegl R, Granacher U. (2021). Home-based exercise programmes improve physical fitness of healthy older adults: A PRISMA-compliant systematic review and meta-analysis with relevance for COVID-19. Ageing research reviews, 101265
• 17 Kong SH, Hwang BK, Yoon B-H. "The Impact of COVID-19 on the Optimal Management of Osteoporosis." Journal of Bone Metabolism 28.2 (2021): 115-122
• 18 Messina C, Buzzoni AC, Gitto S, Almolla J, Albano D, Sconfienza LM. Disruption of bone densitometry practice in a Northern Italy Orthopedic Hospital during the COVID-19 pandemic. Osteoporosis International 2021; 32: 199-203
• 19 McCloskey EV, Harvey NC, Johansson H, Lorentzon M, Vandenput L, Liu E, Kanis JA. Global impact of COVID-19 on non-communicable disease management: descriptive analysis of access to FRAX fracture risk online tool for prevention of osteoporotic fractures. Osteoporos Int. 2021
• 20 Hampson G, Stone M, Lindsay JR, Crowley RK, Ralston SH. (2021). Diagnosis and Management of Osteoporosis During COVID-19: Systematic Review and Practical Guidance. Calcified Tissue International, 1-12
• 21 Paskins Z, Crawford-Manning F, Bullock L, Jinks C. Identifying and managing osteoporosis before and after COVID-19: rise of the remote consultation?. Osteoporosis International 2020; 31: 1629-1632
• 22 van den Berg N, Schumann M, Kraft K, Hoffmann W. Telemedicine and telecare for older patients – a systematic review. Maturitas 2012; 73: 94-114
• 23 Parker S, Prince A, Thomas L, Song H, Milosevic D, Harris MF. Electronic, mobile and telehealth tools for vulnerable patients with chronic disease: a systematic review and realist synthesis. BMJ Open 2018; 8: e019192
• 24 Thomasius F, Baum E, Bernecker P, Böcker W, Brabant T, Clarenz P, Kurth AA. DVO Leitlinie 2017 zur Prophylaxe, Diagnostik und Therapie der Osteoporose bei postmenopausalen Frauen und Männern. Osteologie 2018; 27: 154-160