Noziplastischer Schmerz

Noziplastische Schmerzen sind eine dritte mechanistische Schmerzkategorie. Anders als bei nozizeptiven oder neuropathischen Schmerzen findet sich weder eine Gewebeschädigung, noch eine Läsion im somatosensorischen Nervensystem. Die IASP-Definition erklärt die Pathophysiologie als veränderte Nozizeption infolge einer Modulation der Reizverarbeitung. Die Breite der Definition und ihre nur entfernte Verknüpfung mit neurophysiologischen Mechanismen machen sie allerdings potentiell zum Sammelbecken unspezifischer und unklarer Befunde.

Publication History

Article published online:
05 January 2022

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