Frauenheilkunde up2date 2023; 17(04): 341-357
DOI: 10.1055/a-1718-8159
Allgemeine Gynäkologie

Management des CIN-Rezidivs nach Exzision

Jens Hachenberg
,
Peter Hillemanns
,
Matthias Jentschke
,
Lena Steinkasserer

Die zervikale intraepitheliale Neoplasie (CIN) ist eine Präkanzerose im Gebärmutterhals. Wenn eine CIN 3 diagnostiziert wird, wird in der Regel eine Exzision durchgeführt. Allerdings kann es in einigen Fällen zu einem Rezidiv kommen. Das Management des CIN-Rezidivs nach Exzision ist daher von entscheidender Bedeutung, um sicherzustellen, dass die betroffene Frau die bestmögliche Behandlung erhält.

Kernaussagen
  • Das Rezidivrisiko der CIN 3 nach Exzision beträgt ca. 6% innerhalb von 5 Jahren.

  • Die Therapie eines CIN-Rezidivs ist die operative Re-Exzision.

  • Durch eine postoperative Impfung gegen HPV kann das Risiko eines Rezidivs der CIN signifikant gesenkt werden.

  • Die wichtigsten Komplikationen nach der operativen Therapie sind ein erhöhtes Risiko für Zervixstenosen und Frühgeburtlichkeit.

  • Die Nachsorge besteht aus einer kombinierten Untersuchung mit HPV-Test und Zytologie 6, 12 und 24 Monate nach erfolgter Therapie.



Publikationsverlauf

Artikel online veröffentlicht:
15. August 2023

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