A Homocoupling Approach to the Key Dione of CyMe4-BTPhen – Vital Ligands for Nuclear Clean-Up by the SANEX Process

CyMe₄-BTPhen and CyMe₄-BTBP are the principal ligand systems used in Europe for the separation of actinides from lanthanides as a part of the SANEX process for nuclear recycling and reprocessing. We present a new approach to the synthesis of the CyMe₄ fragment beginning from readily available hydroxypivalic acid. It features a cobalt-catalysed homocoupling of a neopentyl bromide to provide the key bisester precursor, thereby avoiding the requirement for technically challenging low-temperature LDA-mediated aldol chemistries.

Key words

homocoupling - catalysis - nuclear clean-up - elemental separations - SANEX process - accident tolerant fuel

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References

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