Synthesis, Inhaltsverzeichnis Synthesis 2022; 54(13): 3055-3068DOI: 10.1055/a-1747-5457 paper Base/B2pin2-Mediated Iodofluoroalkylation of Alkynes and Alkenes Jianglong Wu , Chenyu Wang , Zhongjie Wang , Hongjun Li , Ruyan Liu , Yan Wang , Pengsheng Zhou , Dianjun Li∗ , Jinhui Yang∗ Artikel empfehlen Abstract Artikel einzeln kaufen Alle Artikel dieser Rubrik Abstract A base/B2pin2-mediated iodofluoroalkylation of alkynes and a part of alkenes, using ethyl difluoroiodoacetate (ICF2CO2Et) or ICnF2n+1 (n = 3, 4, 6) as difluoroacetylating or perfluoroalkylating reagent, is disclosed. The reaction proceeds under mild conditions, and iododifluoroalkylation, hydrodifluoroalkylation and several perfluoroalkylation products were generated from alkynes or alkenes. Notably, this methodology provides a simple access to difluoroalkylated and perfluoroalkylated organic compounds starting from simple alkynes or alkenes. 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