Synthetic Studies on Chromone Natural Products: The Preusso­chromones

Abstract

Total syntheses of preussochromones A, D, E, and F and structural revisions of preussochromones E and F are reviewed, demonstrating the use of α-keto esters and α,β-diketo esters as valuable reactants in stereoselective cyclization reactions in total synthesis.

1 Introduction

2 The Route to Preussochromone D

3 Synthesis and Structural Revision of Preussochromones E and F

4 Total Synthesis of Preussochromone A

5 Conclusion

Key words

natural product synthesis - preussochromone - chromenone - fully substituted cyclopentane - sulfur-containing natural products - keto ester

Publication History

Received: 20 January 2022

Accepted after revision: 14 February 2022

Accepted Manuscript online:
14 February 2022

Article published online:
29 March 2022

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