Am J Perinatol 2023; 40(11): 1173-1177 DOI: 10.1055/a-1787-8099
Partnerships in the Comprehensive Management of Multisystem Inflammatory Syndrome in Neonates (MIS-N): Translating 2 Years of Pediatric Practice to the Neonatal Wards
1
Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy
2
Center for Global Health Research Studies, Università Cattolica del Sacro Cuore, Roma, Italia
3
Dipartimento di Scienze di Laboratorio e Infettivologiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy
› Author Affiliations
References
1
Lakshminrusimha S,
Hudak ML,
Dimitriades VR,
Higgins RD.
Multisystem Inflammatory Syndrome in Neonates following Maternal SARS-CoV-2 COVID-19 Infection. Am J Perinatol 2022; 39 (11) 1166-1171
2
More K,
Aiyer S,
Goti A.
et al.
Multisystem inflammatory syndrome in neonates (MIS-N) associated with SARS-CoV2 infection: a case series. Eur J Pediatr 2022; 181 (05) 1883-1898
3
Patrick AE,
Lyons EM,
Ishii L.
et al.
Case report: infantile urticaria as a herald of neonatal onset multisystem inflammatory disease with a novel mutation in NLRP3. Front Immunol 2021; 12: 775140
4
Bakhle A,
Sreekumar K,
Baracho B,
Sardessai S,
Silveira MP.
Cavitary lung lesions in a neonate: potential manifestation of COVID-19 related multisystem inflammatory syndrome. Pediatr Pulmonol 2022; 57 (01) 311-314
5
Agrawal G,
Wazir S,
Arora A,
Sethi SK.
Multisystem inflammatory syndrome in a neonate masquerading as surgical abdomen. BMJ Case Rep 2021; 14 (10) e246579
6
Amulya GI,
Kaur A,
Sharma M.
Multisystem Inflammatory Syndrome in a Neonate with Prenatal Exposure to COVID-19. Indian J Pediatr 2022; 89 (03) 314
7
Eghbalian F,
Sami G,
Bashirian S,
Jenabi E.
A neonate infected with coronavirus disease 2019 with severe symptoms suggestive of multisystem inflammatory syndrome in childhood. Clin Exp Pediatr 2021; 64 (11) 596-598
8
Amonkar PS,
Gavhane JB,
Kharche SN,
Kadam SS,
Bhusare DB.
Aortic thrombosis in a neonate with COVID-19-related fetal inflammatory response syndrome requiring amputation of the leg: a case report. Paediatr Int Child Health 2021; 41 (03) 211-216
9
Diwakar K,
Gupta BK,
Uddin MW,
Sharma A,
Jhajra S.
Multisystem inflammatory syndrome with persistent neutropenia in neonate exposed to SARS-CoV-2 virus: a case report and review of literature. J Neonatal Perinatal Med 2022; 15 (02) 373-377
10
Saha S,
Pal P,
Mukherjee D.
Neonatal MIS-C: managing the cytokine storm. Pediatrics 2021; 148 (05) e2020042093
11
Diggikar S,
Nanjegowda R,
Kumar A,
Kumar V,
Kulkarni S,
Venkatagiri P.
Neonatal multisystem inflammatory syndrome secondary to SARS-CoV-2 infection. J Paediatr Child Health 2021; 8 (07) 572
12
Pawar R,
Gavade V,
Patil N.
et al.
Neonatal multisystem inflammatory syndrome (MIS-N) associated with prenatal maternal SARS-CoV-2: a case series. Children (Basel) 2021; 8 (07) 572
13
Shaiba LA,
Hadid A,
Altirkawi KA.
et al.
Case Report: neonatal multi-system inflammatory syndrome associated with SARS-CoV-2 exposure in two cases from Saudi Arabia. Front Pediatr 2021; 9: 652857
14
Divekar AA,
Patamasucon P,
Benjamin JS.
Presumptive neonatal multisystem inflammatory syndrome in children associated with coronavirus disease 2019. Am J Perinatol 2021; 38 (06) 632-636
15
Kappanayil M,
Balan S,
Alawani S.
et al.
Multisystem inflammatory syndrome in a neonate, temporally associated with prenatal exposure to SARS-CoV-2: a case report. Lancet Child Adolesc Health 2021; 5 (04) 304-308
16
Khaund Borkotoky R,
Banerjee Barua P,
Paul SP,
Heaton PA.
COVID-19-related potential multisystem inflammatory syndrome in childhood in a neonate presenting as persistent pulmonary hypertension of the newborn. Pediatr Infect Dis J 2021; 40 (04) e162-e164
17
Wohlrab F,
Bauknecht C,
Meisel C,
Dreier JP.
A case of neonatal onset multisystem inflammatory disease supporting a role of interleukin-1β in Moyamoya syndrome. Neurol Neuroimmunol Neuroinflamm 2020; 8 (01) e1-e3
18
Costa S,
Delogu AB,
Bottoni A.
et al.
COVID-19 associated multisystem inflammatory syndrome in a neonate with atypical coronary artery involvement. Am J Perinatol 2022; 39 (14) 1514-1518
19
Verdoni L,
Mazza A,
Gervasoni A.
et al.
An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study. Lancet 2020; 395 (10239): 1771-1778
20
Buonsenso D,
Riitano F,
Valentini P.
Pediatric inflammatory multisystem syndrome temporally related with SARS-CoV-2: immunological similarities with acute rheumatic fever and toxic shock syndrome. Front Pediatr 2020; 8: 574
21
Farooqi KM,
Chan A,
Weller RJ.
et al;
Columbia University Interdisciplinary MIS-C Follow-up Program and the CUIMC Pediatric/Adult Congenital Heart Research Collaborative.
Longitudinal outcomes for multisystem inflammatory syndrome in children. Pediatrics 2021; 148 (02) e2021051155
22
Al-Turkait A,
Szatkowski L,
Choonara I,
Ojha S.
Drug utilisation in neonatal units in England and Wales: a national cohort study. Eur J Clin Pharmacol 2022; 78 (04) 669-677
23
Dworsky ZD,
Roberts JE,
Son MBF,
Tremoulet AH,
Newburger JW,
Burns JC.
Mistaken MIS-C: a case series of bacterial enteritis mimicking MIS-C. Pediatr Infect Dis J 2021; 40 (04) e159-e161
24
Buonsenso D,
Soldati G,
Curatola A.
et al.
Lung ultrasound pattern in healthy infants during the first 6 months of life. J Ultrasound Med 2020; 39 (12) 2379-2388
25
Musolino AM,
Tomà P,
Supino MC.
et al.
Lung ultrasound features of children with complicated and noncomplicated community acquired pneumonia: a prospective study. Pediatr Pulmonol 2019; 54 (09) 1479-1486
26
Buonsenso D,
Tomà P,
Scateni S.
et al.
Lung ultrasound findings in pediatric community-acquired pneumonia requiring surgical procedures: a two-center prospective study. Pediatr Radiol 2020; 50 (11) 1560-1569
27
Buonsenso D,
Musolino A,
Ferro V.
et al.
Role of lung ultrasound for the etiological diagnosis of acute lower respiratory tract infection (ALRTI) in children: a prospective study. J Ultrasound 2022; 25 (02) 185-197
28
Musolino AM,
Boccuzzi E,
Buonsenso D.
et al.
The role of lung ultrasound in diagnosing COVID-19-related multisystemic inflammatory disease: a preliminary experience. J Clin Med 2022; 11 (01) 234
29
McArdle AJ,
Vito O,
Patel H.
et al;
BATS Consortium.
Treatment of multisystem inflammatory syndrome in children. N Engl J Med 2021; 385 (01) 11-22
30
Lei J,
Vermillion MS,
Jia B.
et al.
IL-1 receptor antagonist therapy mitigates placental dysfunction and perinatal injury following Zika virus infection. JCI Insight 2019; 4 (07) e122678
31
Pietrasanta C,
Minoia F,
Torreggiani S.
et al.
When neonatal inflammation does not mean infection: an early-onset mevalonate kinase deficiency with interstitial lung disease. Clin Immunol 2019; 205: 25-28
32
Chevin M,
Chelabi K,
Chabrier S,
Sébire G.
Added value of interleukin-1 blockade to hypothermia in the treatment of neonatal encephalopathy. Am J Obstet Gynecol 2020; 223 (03) 458-460
33
Peciuliene S,
Burnyte B,
Gudaitiene R.
et al.
Perinatal manifestation of mevalonate kinase deficiency and efficacy of anakinra. Pediatr Rheumatol Online J 2016; 14 (01) 19
34
Gambacorta A,
Buonsenso D,
De Rosa G.
et al.
Resolution of giant coronary aneurisms in a child with refractory Kawasaki disease treated with Anakinra. Front Pediatr 2020; 8: 195
35
Lee Y,
Schulte DJ,
Shimada K.
et al.
Interleukin-1β is crucial for the induction of coronary artery inflammation in a mouse model of Kawasaki disease. Circulation 2012; 125 (12) 1542-1550
36
Noval Rivas M,
Lee Y,
Wakita D.
et al.
CD8+ T cells contribute to the development of coronary arteritis in the Lactobacillus casei cell wall extract-induced murine model of Kawasaki disease. Arthritis Rheumatol 2017; 69 (02) 410-421
37
Rosenkranz ME,
Schulte DJ,
Agle LM.
et al.
TLR2 and MyD88 contribute to Lactobacillus casei extract-induced focal coronary arteritis in a mouse model of Kawasaki disease. Circulation 2005; 112 (19) 2966-2973
38
Lee Y,
Wakita D,
Dagvadorj J.
et al.
IL-1 signaling is critically required in stromal cells in Kawasaki disease vasculitis mouse model: role of both IL-1α and IL-1β. Arterioscler Thromb Vasc Biol 2015; 35 (12) 2605-2616
39
Hejazi OI,
Loke YH,
Harahsheh AS.
Short-term cardiovascular complications of multi-system inflammatory syndrome in children (MIS-C) in adolescents and children. Curr Pediatr Rep 2021; 9 (04) 93-103
40
Sözeri B,
Çağlayan Ş,
Atasayan V.
et al.
The clinical course and short-term health outcomes of multisystem inflammatory syndrome in children in the single pediatric rheumatology center. Postgrad Med 2021; 133 (08) 994-1000
41
Osmanov IM,
Spiridonova E,
Bobkova P.
Sechenov StopCOVID Research Team et al.
Risk factors for post-COVID-19 condition in previously hospitalised children using the ISARIC Global follow-up protocol: a prospective cohort study.. Eur Respir J. 2022; Feb 3 59 (02) 2101341
42
Buonsenso D,
Di Giuda D,
Sigfrid L.
et al.
Evidence of lung perfusion defects and ongoing inflammation in an adolescent with post-acute sequelae of SARS-CoV-2 infection. Lancet Child Adolesc Health 2021; 5 (09) 677-680
43
Buonsenso D,
Munblit D,
De Rose C.
et al.
Preliminary evidence on long COVID in children. Acta Paediatr 2021; 110 (07) 2208-2211
44
Buonsenso D,
Costa S,
Giordano L.
et al.
Short- and mid-term multidisciplinary outcomes of newborns exposed to SARS-CoV-2 in utero or during the perinatal period: preliminary findings. Eur J Pediatr 2022; 181 (04) 1507-1520
45
Levy M,
Recher M,
Hubert H.
et al.
Multisystem inflammatory syndrome in children by COVID-19 vaccination status of adolescents in France. JAMA 2022; 327 (03) 281-283
46
Zambrano LD,
Newhams MM,
Olson SM.
et al;
Overcoming COVID-19 Investigators.
Effectiveness of BNT162b2 (Pfizer-BioNTech) mRNA vaccination against multisystem inflammatory syndrome in children among persons aged 12-18 years—United States, July-December 2021. MMWR Morb Mortal Wkly Rep 2022; 71 (02) 52-58
47
Chou J,
Platt CD,
Habiballah S.
et al;
Taking on COVID-19 Together Study Investigators.
Mechanisms underlying genetic susceptibility to multisystem inflammatory syndrome in children (MIS-C). J Allergy Clin Immunol 2021; 148 (03) 732-738.e1
48
Vogel TP,
Top KA,
Karatzios C.
et al.
Multisystem inflammatory syndrome in children and adults (MIS-C/A): Case definition & guidelines for data collection, analysis, and presentation of immunization safety data. Vaccine 2021; 39 (22) 3037-3049
49
Salzman MB,
Huang CW,
O'Brien CM,
Castillo RD.
Multisystem inflammatory syndrome after SARS-CoV-2 infection and COVID-19 vaccination. Emerg Infect Dis 2021; 27 (07) 1944-1948
50
MedRxiv..
Reported Cases of Multisystem Inflammatory Syndrome in Children (MIS-C) Aged 12–20 Years in the United States Who Received COVID-19 Vaccine, December 2020 through August 2021. Accessed on January 15, 2022 at: https://www.medrxiv.org/content/10.1101/2022.01.03.22268681v1