Synthesis of the Icetexane Diterpenoids (±)-Rosmaridiphenol, (±)-Pisiferin, and (±)-Barbatusol from Abietane

Abstract

We report the rearrangement of abietane core with trifluoromethanesulfonic anhydride in pyridine to afford the icetexane core, a key intermediate for total syntheses of the structurally intriguing and biologically active compounds (±)-barbatusol, (±)-rosmaridiphenol, and (±)-pisiferin.

Key words

icetexane - abietane - diterpenoids - pisiferin - rosmaridiphenol - barbatusol - ring expansion

• References and Notes

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