Klin Monbl Augenheilkd 2022; 239(07): 894-898
DOI: 10.1055/a-1806-2405
Kasuistik

Comparison of two Schwann Cell-Containing Orbital Tumors: Schwannoma and Ganglioneuroma

Article in several languages: deutsch | English
1   Klinik für Augenheilkunde, Universitätsklinikum Freiburg, Deutschland
,
Wolf Alexander Lagrèze
1   Klinik für Augenheilkunde, Universitätsklinikum Freiburg, Deutschland
,
Martin Werner
2   Institut für klinische Pathologie, Universitätsklinikum Freiburg, Deutschland
,
Horst Urbach
3   Klinik für Neuroradiologie, Universitätsklinikum Freiburg, Deutschland
,
Michael Reich
1   Klinik für Augenheilkunde, Universitätsklinikum Freiburg, Deutschland
,
1   Klinik für Augenheilkunde, Universitätsklinikum Freiburg, Deutschland
› Author Affiliations

Abstract

Orbital tumors comprise a variety of diseases, although tumors of the peripheral nerves are rare. Of these, schwannoma is considered the most common entity, consisting histopathologically almost exclusively of Schwann cells. Another benign tumor containing Schwann cells is ganglioneuroma. Here, ganglion cells are histopathologically apparent in addition to the Schwann cell-containing stroma. Ganglioneuroma belongs to the group of neuroblastic tumors and can occur anywhere in the pathway of sympathetic ganglion cells. In this report, we present the disease courses as well as the findings of two patients with different orbital tumors. In both cases, the diagnosis was only confirmed by histopathological examination. The first patient had a schwannoma with cystic degeneration and the second patient had a ganglioneuroma, both tumor entities which occur only rarely in the orbit. Commonalities and differences are discussed.



Publication History

Received: 31 December 2021

Accepted: 21 March 2022

Article published online:
20 July 2022

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