Synthesis, Table of Contents Synthesis 2022; 54(17): 3719-3728DOI: 10.1055/a-1811-8503 feature 1,1-Difunctionalization of α‑Carbonyl Sulfur Ylides with Thiosulfonates: Synthesis of β-Keto Thiosulfones Xiaokang Kang , Shuyan Lai , Xiayu Liang , Qingle Zeng ∗ Recommend Article Abstract Buy Article All articles of this category Abstract 1,1-Difunctionalization of α‑carbonyl sulfur ylides and thiosulfonates under simple conditions is disclosed. In this protocol, two new C–S bonds are constructed in a one-step reaction. A series of aliphatic and aromatic β-keto thiosulfones were obtained in moderate to good yields. This reaction probably proceeds through sulfur ylide-involved nucleophilic substitution of an ion pair within a solvent cage. Key words Key words1,1-difunctionalization - sulfur ylides - thiosulfonates - β-keto thiosulfones - organosulfur chemistry Full Text References References 1a Corey EJ, Chaykovsky M. J. Am. Chem. Soc. 1965; 87: 1353 1b Johnson AW, LaCount RB. J. Am. Chem. 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