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DOI: 10.1055/a-1823-1528
Interdisciplinarity in Diagnostics of Bone Lesions
Article in several languages: deutsch | EnglishAbstract
Introduction Due to substantial advances in all medical disciplines, interdisciplinary cooperation is of major relevance in modern medicine. Given the rarity of benign and malignant bone tumours, diagnosis and therapy of these lesions is especially challenging. Focusing on typical cases, it is the aim of this article to illustrate the necessity of interdisciplinary cooperation.
Methods The scope of this article is to highlight the particular significance of interdisciplinarity in the diagnosis of bone tumours. To this end, we illustrate the interdisciplinary approach in typical clinical cases.
Results and Discussion The article demonstrates that a combined clinico-radiological approach is essential in the diagnosis of leave-me-alone lesions, and it underlines the essential role of an interdisciplinary correlation of clinical context, radiology and pathology in the interpretation of bone tumour biopsies. It documents the experience that all clinical aspects and diagnostic findings need to be synoptically integrated in a joint interdisciplinary tumour board to eventually find the correct diagnosis.
Conclusion It is generally accepted that the diagnosis of a bone tumour can often not be made by the pathologist alone but essentially requires interdisciplinary cooperation.
Publication History
Received: 01 September 2021
Accepted after revision: 28 March 2022
Article published online:
22 June 2022
© 2022. Thieme. All rights reserved.
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Literatur
- 1 ESMO/European Sarcoma Network Working Group. Bone sarcomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 2014; 25 (03) iii113-iii123
- 2 Herget GW, Mauer D, Krauss T. et al. Non-ossifying fibroma: natural history with an emphasis on a stage-related growth, fracture risk and the need for follow-up. BMC Musculoskelet Disord 2016; 17: 147
- 3 Hardes J, Gosheger G, Budny T. Knochensarkome. Z Orthop Unfall 2018; 156: 105-124
- 4 Pan KL, Chan WH, Chia YY. Initial symptoms and delayed diagnosis of osteosarcoma around the knee joint. J Orthop Surg (Hong Kong) 2010; 18: 55-57
- 5 Schlegel M, Zeumer M, Prodinger PM. et al. Impact of Pathological Fractures on the Prognosis of Primary Malignant Bone Sarcoma in Children and Adults: A Single-Center Retrospective Study of 205 Patients. Oncology 2018; 94: 354-362
- 6 Vanel D, Ruggieri P, Ferrari S. et al. The incidental skeletal lesion: ignore or explore?. Cancer Imaging 2009; 9: S38-S43
- 7 Freyschmidt J, Ostertag H, Jundt G. Knochentumoren. Klinik, Radiologie, Pathologie. 2. Berlin: Springer; 2003
- 8 Blay JY, Honore C, Stoeckle E. et al. Surgery in reference centers improves survival of sarcoma patients: a nationwide study. Ann Oncol 2019; 30: 1143-1153
- 9 Jakob J, Henzler T, Kasper B. et al. [Interdisciplinary treatment of soft tissue sarcoma of the extremities]. Chirurg 2014; 85: 383-390
- 10 Blay JY, Soibinet P, Penel N. et al. Improved survival using specialized multidisciplinary board in sarcoma patients. Ann Oncol 2017; 28: 2852-2859
- 11 Eichler M, Andreou D, Golcher H. et al. Utilization of Interdisciplinary Tumor Boards for Sarcoma Care in Germany: Results from the PROSa Study. Oncol Res Treat 2021; 44: 301-312
- 12 Jundt G, Baumhoer D. [Pathological assessment of bone sarcomas]. Unfallchirurg 2014; 117: 510-516