Drug Res (Stuttg) 2022; 72(07): 355-366
DOI: 10.1055/a-1824-4619
Review

Nanomedicines: A Focus on Nanomaterials as Drug Delivery System with Current Trends and Future Advancement

Jaya Pandey
1   Amity School of Applied Sciences Lucknow, Amity University Uttar Pradesh, Lucknow Campus, India
,
Ragini Dubey
1   Amity School of Applied Sciences Lucknow, Amity University Uttar Pradesh, Lucknow Campus, India
,
Aditya Kate
2   Amity Institute of Biotechnology, Amity University, Chhattisgarh, India
,
Bhairav Prasad
3   Department of Biotechnology, Chandigarh College of Technology, Landran, Mohali, India
,
Arzoo Sinha
2   Amity Institute of Biotechnology, Amity University, Chhattisgarh, India
,
Mohit S Mishra
2   Amity Institute of Biotechnology, Amity University, Chhattisgarh, India
› Author Affiliations
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Abstract

The rapid advancement of nanomedicine presents novel alternatives that have the potential to transform health care. Targeted drug delivery as well as the synthesis of nanocarriers is a growing discipline that has been intensively researched to reduce the complexity of present medicines in a variety of diseases and to develop new treatment and diagnostic techniques. There are several designed nanomaterials used as a delivery system such as liposomes, micelles, dendrimers, polymers, carbon-based materials, and many other substances, which deliver the drug moiety directly into its targeted body area reducing toxic effect of conventional drug delivery, thus reducing the amount of drug required for therapeutic efficacy and offering many more advantages. Currently, these are used in many applications, including cancer treatment, imaging contrast agents, and biomarker detection and so on. This review provides a comprehensive update in the field of targeted nano-based drug delivery systems, by conducting a thorough examination of the drug synthesis, types, targets, and application of nanomedicines in improving the therapeutic efficiency.

Key words

Nanomedicines - Nanotechnology - Bioavailability - Drug Delivery - Toxicity - Nanomaterials


Publication History

Received: 20 September 2021

Accepted: 05 April 2022

Article published online:
30 May 2022

© 2022. Thieme. All rights reserved.

Georg Thieme Verlag
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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