Spectral CT in Oncology

Julia Sauerbeck; Gerhard Adam; Mathias Meyer

doi:10.1055/a-1902-9949

RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, Table of Contents

Rofo 2023; 195(01): 21-29
DOI: 10.1055/a-1902-9949

Review

Onkologische Bildgebung mittels Spektral-CT

Article in several languages: English | deutsch

Julia Sauerbeck

Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, Hamburg, Germany

,

Gerhard Adam

Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, Hamburg, Germany

,

Mathias Meyer

Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, Hamburg, Germany

› Author Affiliations

Abstract

Zusammenfassung

Hintergrund Die Spektral-CT gewinnt mit vielfältigen Einsatzmöglichen zunehmend an klinischer Bedeutung, so auch im Rahmen der onkologischen Bildgebung. Die Spektral-CT-spezifischen Bilddaten bieten durch verschiedene Nachbearbeitungsalgorithmen vielfältige Vorteile gegenüber konventionellen CT-Bilddaten, was im folgenden Review genauer beleuchtet werden soll.

Methodik Der vorliegende Review-Artikel soll einen Überblick über die potenziell nützlichsten onkologischen Anwendungsgebiete der Spektral-CT geben und auf spezifische Spektral-CT-Fallstricke hinweisen. Hierbei werden sowohl technische Hintergründe als auch klinische Vorteile von onkologischen Primär- und Verlaufsuntersuchungen mittels Spektral-CT beleuchtet und die Anwendung entsprechender Spektral-Tools erläutert.

Ergebnisse/Schlussfolgerungen Die Spektral-CT-Bildgebung bietet vielfältige Vorteile gegenüber der konventionellen CT-Bildgebung, insbesondere auf dem Gebiet der Onkologie. Die Kombination von virtuell nativen und niedrigenergetischen Bildern führt zu einer verbesserten Detektion und Charakterisierung von Tumorläsionen. Jodkarten-Bilder bieten einen potenziellen Imaging-Biomarker zur Beurteilung des Therapieansprechens.

Kernaussagen

Die wichtigsten Spektral-CT-Rekonstruktionen für die onkologische Bildgebung sind die virtuell nativen, Jodkarten- und virtuelle monochromatische Rekonstruktionen.
Die Kombination aus virtuell nativen und niedrigenergetischen Bildern führt zu einer verbesserten Detektion und Charakterisierung von vaskularisierten und nicht vaskularisierten Läsionen.
Jodkarten können ein Surrogatparameter für die Tumorperfusion sein und potenziell als Therapie-Monitoring-Parameter verwendet werden.
Für die Strahlentherapie-Planung lassen sich die relative Elektronendichte und die effektive Ordnungszahl eines Gewebes berechnen.

Zitierweise

Sauerbeck J, Adam G, Meyer M. Spectral CT in Oncology. Fortschr Röntgenstr 2023; 195: 21 – 29

Key words

therapy planning - oncology imaging - lesion detection - review - CT - spectral CT

Full Text

References

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