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CC BY-NC-ND 4.0 · Endoscopy 2022; 54(S 02): E1032-E1033
DOI: 10.1055/a-1913-7857
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Gastric peroral endoscopic myotomy for the resection of a predominantly extraluminal submucosal tumor in the duodenal bulb

Li Wang‡   *
1   Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China
,
Zu-Qiang Liu‡   *
1   Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China
,
Quan-Lin Li
1   Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China
2   Shanghai Collaborative Innovation Center of Endoscopy, Shanghai, China
,
Ping-Hong Zhou
1   Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China
2   Shanghai Collaborative Innovation Center of Endoscopy, Shanghai, China
› Author AffiliationsSupported by: National Natural Science Foundation of China http://dx.doi.org/10.13039/501100001809 82000507
Supported by: Youth Foundation of Zhongshan Hospital, Fudan University 2020ZSQN16
Supported by: Yangfan Program of Shanghai Municipal Science and Technology Committee S2020-016
Supported by: National Key R&D Program of China 2019YFC1315800
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A 53-year-old man was admitted with a duodenal submucosal tumor ([Fig. 1 a,b]) that had been detected on a regular physical examination. Because the tumor was located on the posterior wall of the duodenal bulb near the pylorus and had predominantly extraluminal growth, it would have been difficult to perform endoscopic full-thickness resection and close the wound. Therefore, we proposed performing a gastric peroral endoscopic myotomy (G-POEM), which allowed the tumor to be removed using the tunnel technique, while maintaining the integrity of the duodenal mucosa ([Video 1]).

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Fig. 1 Images during the resection of a duodenal submucosal tumor situated close to the pylorus showing: a the submucosal tumor in the duodenal bulb (arrow) on endoscopic ultrasound; b the tumor appearance with well-defined borders on endoscopy; c a 2-cm mucosal incision that was made on the posterior wall 3 cm above the pylorus; d the submucosal tunnel that was created to the pyloric ring (arrow); e partial pyloromyotomy of the circular muscle (arrow); f the tumor (arrow), which originated from the deep layer of the muscularis propria with extraluminal growth; g the resection site after hemostasis had been achieved with hot biopsy forceps; h clip closure of the mucosal entry site in the stomach. i Macroscopic appearance of the tumor specimen, which was 1.8 × 1.5 cm in size.

Video 1 The application of gastric peroral endoscopic myotomy (G-POEM) for resection of a submucosal tumor in the duodenal bulb, which allowed the tumor to be resected using the tunnel technique and maintained the integrity of the duodenal mucosa.


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After the submucosal injection had been performed, a 2-cm mucosal incision was made on the posterior wall 3 cm above of pylorus ([Fig. 1 c]). The submucosal tunnel was created, extending to the pyloric ring ([Fig. 1 d]). After the pyloric ring had been identified, partial pyloromyotomy was performed on the circular muscle ([Fig. 1 e]) to expand the visual field and explore the tumor. The tunnel was extended to the duodenal bulb and we observed that the tumor originated from the deep layer of the muscularis propria with extraluminal growth ([Fig. 1 f]). The tumor was gradually separated with an IT knife combined with a hook knife, then the tumor was removed en bloc with a snare. After hemostasis had been achieved with hot biopsy forceps ([Fig. 1 g]), the mucosal entry point in the stomach was closed with clips ([Fig. 1 h]). The size of tumor was 1.8 × 1.5 cm ([Fig. 1 i]) and postoperative pathology showed a gastrointestinal stromal tumor. The patient recovered uneventfully and was discharged on postoperative day 3. Postoperative endoscopy and a computed tomography scan showed no recurrence 3 months after surgery.

G-POEM was traditionally a treatment for gastroparesis [1] [2]. We recommend a novel application of G-POEM for the resection of a submucosal tumor in the duodenal bulb, which allowed the tumor to be resected using the tunnel technique, thereby maintaining the integrity of the duodenal mucosa and reducing the possibility of complications.

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* Joint first authors




Publication History

Article published online:
25 August 2022

© 2022. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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  • References

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